Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Patent
1998-09-10
2000-08-22
Patterson, Jr., Charles L.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
424 944, C12N 902
Patent
active
06107070&
ABSTRACT:
Human manganese superoxide dismutase (hMn SOD) having catalytic activity which differs from natural hMn SOD is disclosed. The hMn SOD of the invention exhibits reduced or no product inhibition compared to natural hMn SOD, while preferably maintaining equal or improved catalytic activity. The hMn SOD of the invention can be used as an antioxidant to prevent or treat cytotoxicity resulting from oxidation.
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Nick Harry S.
Silverman David N.
Patterson Jr. Charles L.
Remillard, Esq. Jane E.
University of Florida
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