Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1986-06-06
1990-01-30
Tarcza, John
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
424 85, 935107, 530809, A61K 39395
Patent
active
048974668
ABSTRACT:
A 6-thioguanine-resistant subvariant of the EBV-transformed human lymphoblastoid B cell line WI-L2 is described. The subvariant line, designated LTR228, fuses efficiently with human cells. Human.times.human hybridomas derived from LTR228 that produce monoclonal antibodies against tetanus toxin and blood group A are exemplified.
REFERENCES:
patent: 4451570 (1984-05-01), Royston et al.
patent: 4624921 (1986-11-01), Larrick et al.
Kozbor et al., "Human Hybridomas Constructed with Antigen-Specific Epstein-Barr Virus Transformed Cell Lines" Proc. Natl. Acad. Sci. U.S.A. 79, pp. 6651-6655 (1982).
Physicians Desk Reference, 31st ed. Litton Industries, p. 1382 (1977).
Choy et al., "Techniques for Using HAT Selection in Somatic Cell Gentics", Techniques in Somatic Cell Genetics, ed. Shay, Plenum Press, N.Y., pp. 11-21 (1982).
Chiorazzi, N., et al., J. Exp. Med. (1982) 156:930-935.
Handley, H. H., et al., Proceedings of the 15th International Leucocyte Culture Conference, Asilomar (1982), p. 267.
Larrick James W.
Raubitschek Andrew R.
Truitt Kenneth E.
Cetus Corporation
Giotta Gregory J.
Hasak Janet E.
Murphy Lisabeth F.
Tarcza John
LandOfFree
Human lymphoblastoid cell line and hybridomas derived therefrom does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Human lymphoblastoid cell line and hybridomas derived therefrom, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human lymphoblastoid cell line and hybridomas derived therefrom will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1924151