Human lymph node derived GTPase

Details Human lymph node derived GTPase Human lymph node derived GTPase

1998-01-13

1999-10-12

Elliot, George C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 6, 435440, 435455, 435325, 435243, 4353201, 536 231, 536 232, 536 235, 536 245, 536 2432, C12P 1934, C07H 2104, C07H 2102, C12N 1511

Patent

active

059653965

ABSTRACT:
A novel human GTPase polypeptide intracellular molecular switch is described. A full length cDNA which encodes the signal transduction polypeptide is disclosed as well as the interior structural region and the amino acid residue sequence of the human GTPase. Methods are provided to identify compounds that modulate the biological activity of the native signal switch biomolecule and hence regulate cellular and tissue physiology.

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