Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Patent
1998-03-05
2000-04-04
LeGuyader, John L.
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
435 6, 435325, 435370, 435375, 435455, 536 245, C12N 1585, C12N 1500, C12Q 168, C07H 2104
Patent
active
060460504
ABSTRACT:
The invention refers to a new human liver cell line which may be used for toxicological, physiological and, in particular, gene therapeutic examinations. Fields of application are molecular biology, medicine and pharmaceutical industry. The new human liver cell line is marked positive owing to the parameters albumin and alpha-1-antitrypsin (ATT) and negative owing to alpha-fetoprotein (AFP). It has been deposited in the Deutsche Sammlung von Mikroorganismen (DSM ACC2302).
REFERENCES:
Woodworth et al. Molecular and Cellular Biology, Oct. 1988, vol. 8, No. 10, pp. 4492-4501.
Wu et al. Cancer Research, Nov. 1994, vol. 54, pp. 5964-5973.
Kirillowa Ira
Strauss Michael
HepaVec AG fur Gentherapie
LeGuyader John L.
Shibuya Mark L.
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