Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-12-08
2000-04-04
Caputa, Anthony C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 435325, 536 231, 536 235, C12N 1512, C12N 1585, C12N 1563, C07H 2104
Patent
active
06046030&
ABSTRACT:
HLIG-1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HLIG-1 polypeptides and polynucleotides in the design of protocols for the treatment of neurological disorders such as Alzheimer's disease, multiple sclerosis and abnormal neural development; endocrine disorders such as diabetes; and heart disease, among others and diagnostic assays for such conditions.
REFERENCES:
GenBank Accession #D78572.
GenBank Accession #X53959.
GenBank Accession #P35859.
GenBank Accession #U11052.
GenBank Accession #X66494.
Y. Suzuki, et al., "cDNA Cloning of a Novel Membrane Glycoprotein That Is Expressed specifically in Glial Cells in the Mouse Brain", J. Biol. Chem., vol. 271, pp. 22522-22527 (1996).
J. Dai, et al., "Molecular Cloning Of The Acid-Labile Subunit Of The Rat Insulin-Like Growth Factor Binding Protein Complex", Biochem Biophys. Res. Commun., vol. 188, pp. 304-309 (1992).
J.M. Rothberg, et al., "slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains" Genes & Development, vol. 4, pp. 2169-2187 (1990).
R.E. Nelson et al., "Peroxidasin: a novel enzyme-matrix protein of Drosophila development", EMBO J., vol. 13, pp. 3438-3447 (1994).
W.Mayser et al., "Primary structure and functional expression of a choline transporter expressed in the rat nervous system", FEBS Lett., vol. 305, pp. 31-36 (1992).
Human Genome Sciences EST #231054.
Genbank Accession #V04445.
Lewin, Genes IV (1990) Oxford University Press, NY pp. 75-77.
Schlesinger (ed); George et al, "Current Methods in Sequence Comparison and Analysis" Macromolecular Sequencing and Synthesis, (1988) 127-149.
Sweet Raymond W
Truneh Alemseged
Wu Shujian
Caputa Anthony C.
Gucker Stephen
Han William T.
King William T.
SmithKline Beecham Corporation
LandOfFree
Human LIG-1 homolog (HLIG-1) does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Human LIG-1 homolog (HLIG-1), we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human LIG-1 homolog (HLIG-1) will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-364137