Human leucine-rich repeat-containing proteins specifically...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S006120, C435S069100, C435S320100, C435S325000, C514S012200, C530S350000, C530S388100, C536S023500

Reexamination Certificate

active

07141381

ABSTRACT:
The present invention describes two newly discovered Human Leucine Rich Repeat (LRR)-containing proteins, HLRRNS-2 and HLRRNS-3, and their encoding polynucleotides. Also described are expression vectors, host cells, agonists, antagonists, antisense molecules, and antibodies associated with the polynucleotides and/or polypeptides of the present invention. In addition, methods involving the new HLRR-containing proteins HLRRNS-2 and HLRRNS-3, or modulators thereof, for treating, diagnosing, preventing, and screening for disorders associated with aberrant cell growth, neurological conditions, and diseases or disorders related to the brain are illustrated.

REFERENCES:
patent: 2003/0027988 (2003-02-01), Baker et al.
patent: 2003/0036635 (2003-02-01), Baker et al.
patent: 2003/0044934 (2003-03-01), Baker et al.
patent: 2003/0045687 (2003-03-01), Baker et al.
patent: 2003/0050448 (2003-03-01), Baker et al.
patent: 2003/0065147 (2003-04-01), Baker et al.
patent: 2003/0069397 (2003-04-01), Baker et al.
patent: 2003/0073814 (2003-04-01), Baker et al.
patent: 2003/0073816 (2003-04-01), Baker et al.
patent: 2003/0073817 (2003-04-01), Baker et al.
patent: 2003/0088063 (2003-05-01), Baker et al.
patent: 2003/0088064 (2003-05-01), Baker et al.
patent: 2003/0088065 (2003-05-01), Baker et al.
patent: 2003/0088066 (2003-05-01), Baker et al.
patent: 2003/0088067 (2003-05-01), Baker et al.
patent: 2003/0088068 (2003-05-01), Baker et al.
patent: 2003/0088070 (2003-05-01), Baker et al.
patent: 2003/0088071 (2003-05-01), Baker et al.
patent: 2003/0088072 (2003-05-01), Baker et al.
patent: 2003/0092886 (2003-05-01), Baker et al.
patent: 2003/0092887 (2003-05-01), Baker et al.
patent: 2003/0092888 (2003-05-01), Baker et al.
patent: 2003/0092889 (2003-05-01), Baker et al.
patent: 2003/0092890 (2003-05-01), Baker et al.
patent: 2003/0096362 (2003-05-01), Baker et al.
patent: 2003/0096959 (2003-05-01), Baker et al.
patent: 2003/0096960 (2003-05-01), Baker et al.
patent: 2003/0096961 (2003-05-01), Baker et al.
patent: 2003/0096962 (2003-05-01), Baker et al.
patent: 2003/0096963 (2003-05-01), Baker et al.
patent: 2003/0096964 (2003-05-01), Baker et al.
patent: 2003/0096965 (2003-05-01), Baker et al.
patent: 2003/0096966 (2003-05-01), Baker et al.
patent: 2003/0096967 (2003-05-01), Baker et al.
patent: 2003/0096968 (2003-05-01), Baker et al.
patent: 2003/0096969 (2003-05-01), Baker et al.
patent: 2003/0096970 (2003-05-01), Baker et al.
patent: 2003/0096971 (2003-05-01), Baker et al.
patent: 2003/0096972 (2003-05-01), Baker et al.
patent: 2003/0100064 (2003-05-01), Baker et al.
patent: 2003/0100708 (2003-05-01), Baker et al.
patent: 2003/0100709 (2003-05-01), Baker et al.
patent: 2003/0100710 (2003-05-01), Baker et al.
patent: 2003/0100711 (2003-05-01), Baker et al.
patent: 2003/0100712 (2003-05-01), Baker et al.
patent: 2003/0100713 (2003-05-01), Baker et al.
patent: 2003/0100714 (2003-05-01), Baker et al.
patent: 2003/0100715 (2003-05-01), Baker et al.
patent: 2003/0100716 (2003-05-01), Baker et al.
patent: 2003/0100717 (2003-05-01), Baker et al.
patent: 2003/0100718 (2003-05-01), Baker et al.
patent: 2003/0100719 (2003-05-01), Baker et al.
patent: 2003/0100720 (2003-05-01), Baker et al.
patent: 2003/0100721 (2003-05-01), Baker et al.
patent: 2003/0100722 (2003-05-01), Baker et al.
patent: 2003/0100723 (2003-05-01), Baker et al.
patent: 2003/0100724 (2003-05-01), Baker et al.
patent: 2003/0100725 (2003-05-01), Baker et al.
patent: 2003/0100726 (2003-05-01), Baker et al.
patent: 2003/0100727 (2003-05-01), Baker et al.
patent: 2003/0100728 (2003-05-01), Baker et al.
patent: 2003/0100729 (2003-05-01), Baker et al.
patent: 2003/0100730 (2003-05-01), Baker et al.
patent: 2003/0100731 (2003-05-01), Baker et al.
patent: 2003/0100732 (2003-05-01), Baker et al.
patent: 2003/0100733 (2003-05-01), Baker et al.
patent: 2003/0100734 (2003-05-01), Baker et al.
patent: 2003/0100735 (2003-05-01), Baker et al.
patent: 2003/0100736 (2003-05-01), Baker et al.
patent: 2003/0100737 (2003-05-01), Baker et al.
patent: 2003/0100738 (2003-05-01), Baker et al.
patent: 2003/0105288 (2003-06-01), Baker et al.
patent: 2003/0105289 (2003-06-01), Baker et al.
patent: 2003/0105290 (2003-06-01), Baker et al.
patent: 2003/0105291 (2003-06-01), Baker et al.
patent: 2003/0220263 (2003-11-01), Feder et al.
patent: 2004/0006206 (2004-01-01), Baker et al.
patent: 2004/0018594 (2004-01-01), Alsobrook, II et al.
patent: 2004/0019183 (2004-01-01), Baker et al.
patent: 2004/0044179 (2004-03-01), Baker et al.
patent: 2004/0044180 (2004-03-01), Baker et al.
patent: 1 270 724 (2003-01-01), None
patent: WO 01/34769 (2001-05-01), None
patent: WO 01/66690 (2001-09-01), None
patent: WO 01/77137 (2001-10-01), None
patent: WO 02/08288 (2002-01-01), None
patent: WO 02/20569 (2002-03-01), None
patent: WO 02/090504 (2002-11-01), None
patent: WO 03/004615 (2003-01-01), None
patent: WO 03/035831 (2003-05-01), None
patent: WO 03/059256 (2003-07-01), None
patent: WO 03/104429 (2003-12-01), None
Kobe et al., Trends Biochem. Sci. 1994, vol. 19(10), pp. 415-421.
Chen, G. et al. Molecular and Cellular Proteomics, 2002, vol. 1, pp. 304-313.
Andreasen et al. Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease. Arch. Neurol. Jun.56(6):673-80, 1999.
Michell et al. Biomarkers and Parkinson's Disease. Brain. Aug; 127: 1693-1705, 2004.
Mickle JE et al. Genotype-phenotype relationships in cystic fibrosis. Med Clin North Am. May 2000;84(3):597-607.
Voet et al. Biochemistry. 1990. John Wiley & Sons, Inc. 126-128 and 228-234.
Yan et al. Two-amino acid molecular switch in a epithelial morphogen that regulates binding to two distinct receptors. Science 290: 523-527, 2000.
NCBI Entrez Accession No. gilNP—115928, Aruga, J. et al., Dec. 22, 2003.
NCBI Entrez Accession No. gil11877257, Heath, P., Dec. 16, 2000.
NCBI Entrez Accession No. gil14017925, Nagase, T. et al., Jun. 5, 2001.
NCBI Entrez Accession No. gil18073098, Redolfi, E. et al., Jan. 4, 2002.
NCBI Entrez Accession No. gil20984229, NCBI Annotation Project, Nov. 18, 2002.
NCBI Entrez Accession No. gil21749288, Suzuki, O. et al., Jul. 15, 2002.
NCBI Entrez Accession No. gil23342567, Parham, C.L. et al., Sep. 26, 2002.
NCBI Entrez Accession No. gil25031235, Oct. 30, 2003.
NCBI Entrez Accession No. gil37546329, Oct. 17, 2003.
Aruga, J. et al., “Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue”, Gene, vol. 315, pp. 87-94 (2003).
Nagase, T. et al., “Prediction of the Coding Sequences of Unidentified Human Genes. XX. The Complete Sequences of 100 New cDNA Clones from Brain Which Code for Large Proteinsin vivo”, DNA Research, vol. 8, pp. 85-95 (2001).
NCBI Entrez Accession No. gil26328293, Carninci, P. et al., Apr. 3, 2004.
NCBI Entrez Accession No. gilNP—079269, Clark, H.F. et al., Jun. 24, 2004.
Swiss-Prot Accession No. Q8JZS8, Release 22, Oct. 2002.
NCBI Entrez Accession No. AAB45703 (gi:1831249), Hudson, D. et al., Feb. 7, 1997.
NCBI Entrez Accession No. AAB50905 (gi:1911844), Heid, H.W. et al., Mar. 28, 1997.
NCBI Entrez Accession No. AAB61227 (gi:2196755), Corbo, J.C. et al., Jun. 15, 1997.
NCBI Entrez Accession No. AAB61228 (gi:2196757), Ropp, P.A. et al., Oct. 27, 1999.
NCBI Entrez Accession No. AAE01312 (gi:5941780), Gruenwald, S. et al., Sep. 29, 1999.
NCBI Entrez Accession No. AAE06789 (gi:5954285), Vlasuk, G. et al., Sep. 29, 1999.
NCBI Entrez Accession No. AAE06798 (gi:5954294), Vlasuk, G. et al., Sep. 29, 1999.
NCBI Entrez Accession No. AAO67545 (gi:29540614), Lauren, J. et al., Apr. 16, 2003.
NCBI Entrez Accession No. AAO67552 (gi:29542647), Lauren, J. et al., Apr. 16, 2003.
NCBI Entrez Accession No. AK056644 (gi:16552103), Ota, T. et al., Jan. 30, 2004.
NCBI Entrez Accession No. AY182024 (gi:29540613), Lauren, J. et al., Apr. 2003.
NCBI Entrez Accession No. BAB71240 (gi:16552104), Ota, T. et al., Jan. 30, 2004.
NCBI Entrez Accession No. CAB63072 (gi:6572272), Corby, N., Jan. 12, 2001.
NCBI Entrez Ac

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