Human ion-exchanger proteins

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Reexamination Certificate

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07057029

ABSTRACT:
Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

REFERENCES:
patent: 4215051 (1980-07-01), Schroeder et al.
patent: 4376110 (1983-03-01), David et al.
patent: 4594595 (1986-06-01), Struckman
patent: 4631211 (1986-12-01), Houghten
patent: 4689405 (1987-08-01), Frank et al.
patent: 4713326 (1987-12-01), Dattagupta et al.
patent: 4873191 (1989-10-01), Wagner et al.
patent: 4946778 (1990-08-01), Ladner et al.
patent: 5252743 (1993-10-01), Barrett et al.
patent: 5272057 (1993-12-01), Smulson et al.
patent: 5424186 (1995-06-01), Fodor et al.
patent: 5445934 (1995-08-01), Fodor et al.
patent: 5459127 (1995-10-01), Felgner et al.
patent: 5556752 (1996-09-01), Lockhart et al.
patent: 5700637 (1997-12-01), Southern
patent: 5744305 (1998-04-01), Fodor et al.
patent: 5830721 (1998-11-01), Stemmer et al.
patent: 5837458 (1998-11-01), Minshull et al.
patent: 5869336 (1999-02-01), Meyer et al.
patent: 5877397 (1999-03-01), Lonberg et al.
patent: 5948767 (1999-09-01), Scheule et al.
patent: 6075181 (2000-06-01), Kucherlapati et al.
patent: 6110490 (2000-08-01), Thierry
patent: 6150584 (2000-11-01), Kucherlapati et al.
Li, X.-F. et al, Molecular cloning of a fourth member of the potassium-dependent sodium-calcium exchanger gene family, NCKX4. J. Biol. Chem. 277:48410-48417, 2002.
Lytton et al, K+-dependent Na+/Ca2+ exchangers in the brain. Ann. N. Y. Acad. Sci. 976:382-393, 2002.
Bird et al, 1988, “Single-Chain Antigen-Binding Proteins”, Science 242:423-426.
Bitter et al, 1987, “Expression and Secretion Vectors for Yeast”, Methods in Enzymology 153:516-544.
Colbere-Garapin et al, 1981, “A New Dominant Hybrid Selective Marker for Higher Eukaryotic Cells”, J. Mol. Biol. 150:1-14.
Gautier et al, 1987, “α-DNA IV:α-anomeric and β-anomeric tetrathymidylates covalently linked to intercalating oxazolopyridocarbazole. Synthesis, physiochemical properties and poly (rA) binding”, Nucleic Acids Research 15(16):6625-6641.
Gordon, 1989, “Transgenic Animals”, International Review of Cytology, 115:171-229.
Greenspan et al, 1993, “Idiotypes: structure and immunogenicity”, FASEB Journal 7:437-444.
Gu et al, 1994, “Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting”, Science 265:103-106.
Huse et al, 1989, “Generation of a Large Combinatorial Library of the Immunoglobulin Repertoire in Phage Lambda”, Science 246:1275-1281.
Huston et al, 1988, “Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain Fv analogue produced inEscherichia coli”, Proc. Natl. Acad. Sci. USA 85:5879-5883.
Inoue et al, 1987, “Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and R Nase H”, FEBS Letters 215(2):327-330.
Inoue et al, 1987, “Synthesis and hybridization studies on two complementary nona(2′-O-methyl)ribonucleotides”, Nucleic Acids Research 15(15):6131-6149.
Inouye & Inouye, 1985, “Up-promoter mutations in the Ipp gene ofEscherichia coli”, Nucleic Acids Research 13(9):3101-3110.
Janknecht et al, 1991, “Rapid and efficient purification of native histidine-tagged protein expressed by recombinant vaccinia virus”, PNAS 88:8972-8976.
Kohler & Milstein, 1975, “Continuous cultures of fused cells secreting antibody of predefined specificity”, Nature 256:495-497.
Lakso et al, 1992, “Targeted oncogene activation by site-specific recombination in transgenic mice”, Proc. Natl. Acad. Sci. USA 89:6232-6236.
Lavitrano et al, 1989, “Sperm Cells as Vectors for Introducing Foreign DNA into Eggs: Genetic Transformation of Mice” Cell 57:717-723.
Lo, 1983, “Transformation by Iontophoretic Microinjection of DNA: Multiple Integrations without Tandem Insertions”, Mol. & Cell. Biology 3(10):1803-1814.
Logan et al, 1984, “Adenovirus tripartite leader sequence enhances translation of mRNAs late after infection”, Proc. Natl. Acad. Sci. USA 81:3655-3659.
Lowy et al, 1980, “Isolation of Transforming DNA: Cloning the Hamster aprt Gene”, Cell 22:817-823.
Morrison et al, 1984, “Chimeric human antibody molecules: Mouse antigen-binding domains with human constant region domains”, Proc. Natl. Acad. Sci. USA 81:6851-6855.
Mulligan & Berg, 1981, “Selection for animal cells that express theEscherichia coligene coding for xanthine-guanine phosphoribosyltransferase”, Proc. Natl. Acad. Sci. USA 78(4):2072-2076.
Neuberger et al, 1984, “Recombinant antibodies possessing novel effector functions”, Nature 312:604-608.
Nisonoff, 1991, “Idiotypes: Concepts and Applications”, J. of Immunology 147:2429-2438.
O'Hare et al, 1981, “Transformation of mouse fibroblasts to methotrexate resistance by a recombinant plasmid expressing a prokaryotic dihydrofolate reductase”, Proc. Natl. Acad. Sci. USA 78(3):1527-1531.
Ruther et al, 1983, “Easy identification of cDNA clones”, EMBO Journal 2(10):1791-1794.
Santerre et al, 1984, “Expression of prokaryotic genes for hygromycin B and G418 resistance as dominant-selection markers in mouse L cells”, Gene 30:147-156.
Sarin et al, 1988, “Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates”, Proc. Natl. Acad. Sci. USA 85:7448-7451.
Smith et al, 1983, “Molecular Engineering of the Autographa californica Nuclear Polyhedrosis Virus Genome: Deletion Mutations within the Polyhedrin Gene”, J. Virol. 46(2):584-593.
Stein et al, 1988, “Physiochemical properties of phosphorothioate oligodeoxynucleotides”, Nucleic Acids Research 16(8):3209-3221.
Szybalska & Szybalski, 1962, “Genetics of Human Cell Lines, IV. DNA-Mediated Heritable Transformation of a Biochemical Trait”, Proc. Natl. Acad. Sci. USA 48:2026-2034.
Takeda et al, 1985, “Construction of chimaeric processed immunoglobulin genes containing mouse variable and human constant region sequences”, Nature 314:452-454.
Thompson et al, 1989, “Germ Line Transmission and Expression of a Corrected HPRT Gene Produced by Gene Targeting in Embryonic Stem Cells”, Cell 56:313-321.
Van Der Putten et al, 1985, “Efficient insertion of genes into the mouse germ line via retroviral vectors”, Proc. Natl. Acad. Sci. USA 82:6148-6152.
Van Heeke et al, 1989, “Expression of Human Asparagine Synthetase inEscherichia coli”, J. Biol. Chemistry 264(10):5503-5509.
Ward et al, 1989, “Binding activities of a repertoire of single immunoglobulin variable domains secreted fromEscherichia coli”, Nature 341:544-546.
Wigler et al, 1977, “Transfer of Purified Herpes Virus Thymidine Kinase Gene to Cultured Mouse Cells”, Cell 11:223-232.
Wigler et al, 1980, “Transformation of mammalian cells with an amplifiable dominant-acting gene”, Proc. Natl. Acad. Sci. USA 77(6):3567-3570.
Database EMBL ‘Online’ KRAEV et al., “Homo sapienspotassium-dependent Na/Ca exchanger NCKX3 (SLC24A3) mRNA,” Sep. 15, 2000, database accession No. AF169257, XP002220751, abstract.
Kraev et al., “Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3,” J. Biol. Chem., vol. 276, No. 25, Jun. 22, 2001, pp. 23161-23172, XP002220750.
Database EMBL ‘Online’ Arakawa et al., “Mus musculus ault retina cDNA,” Jul. 2, 2000, database accession No. BB278154, XP002220752, abstract.
International Search Report, International Application No. PCT/US01/29828, Sep. 24, 2001.

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