Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-05-30
1999-09-28
Ulm, John
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 691, 4352523, 4353201, 435325, 935 27, 935 36, 935 55, 935 56, G01N 3353
Patent
active
059587075
ABSTRACT:
Stably-transformed human cell lines containing a reporter gene operatively linked to an IL-4-responsive element are provided. In some embodiments a human Fc.sub..epsilon. RII IL-4-responsive element is used. In other embodiments a human germline .epsilon. transcript promoter is used as the responsive element. Also provided are methods for using such transformed cell lines to screen for agonists and/or antagonists of human interleukin-4.
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de Vries Jan E.
Jenh Chung-Her
Narula Satwant K.
Zavodny Paul J.
Dulak Norman C.
Mertz Prema
Schering Corporation
Thampoe Immac J.
Ulm John
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