Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1993-12-03
1997-06-17
Ulm, John
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 71, 435 72, 435 691, 4352523, 4353201, 530350, 536 235, C07K 14705, C12N 510, C17N 1512, G01N 3353
Patent
active
056396058
ABSTRACT:
Nucleic acids encoding the .alpha. chain of the human interleukin-3 (IL-3) receptor, as well as the .alpha. chain itself, are provided. The .alpha. chain may be expressed with the .beta. chain in cellular hosts to form compositions useful in screening agonists and antagonists of human IL-3.
REFERENCES:
Kaczmarski et al, Blood Rev 5(3) 1991, pp. 193-203.
Katamura et al, Blood 80(1) 1992, pp. 84-90.
Gearing et al, EMBO J. vol. 8, 1989, pp. 3667-3676.
Itoh et al, Science vol. 247, pp. 324-327, 1990.
Hyashida et al, PNAS 87, 1990, pp. 9655-9659.
Gorman et al PNAS 87, 1990, pp. 5459-5463.
Gesner et al, Blood 74(8) 1989, pp. 2652-2656.
Urdal et al, NY Acad. Science 554, 1989, pp. 167-176.
Reerk et al, Cell 50, 1987, p. 667.
Levin, Science 237, 1987.
Borgmann et al., Nature 319 1986, pp. 226-230 (sequence comparison only).
Yamamoto et al, Nature 319, 1986, pp. 230-234.
Nucleic Acids Res. 13:1505-13 (May 1985) Shimuzu et al. Nucleotide sequence of mouse IL-2 receptor cDNA and its comparison with the human IL-2 receptor sequence.
Cell 60: 941-51 (Mar. 23, 1990) Goodwin et al. Cloning of the Human and Murine Interleukin-7 Receptors: Demonstration of a Soluble Form and Homology . . .
P.N.A.S. 86:8946-50 (Nov. 1989) Sims et al. Cloning the interleukin1 receptor from human T cells.
Kitamura, et al. "Expression Cloning of the Human IL-3 Receptor cDNA Reveals a Shared Beta Subunit for the Human IL-3 and GM-CSF Receptors," Cell, 66(6): 1165-1174, Sep., 1991.
Kuwaki, et al. "Characterization of Human Interleukin-3 Receptors on a Multifactor-Dependent Cell Line," Biochemical and Biophysical Research Communications, 161(1):16-22, May, 1989.
Kitamura Toshio
Miyajima Atsushi
Ching Edwin P.
Dulak Norman C.
Macevicz Stephen C.
Schering Corporation
Ulm John
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