Human interferon-.beta. (IFN-.beta.) produced in Chinese hamster

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Rodent cell – per se

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435 6951, 424 856, 935 34, C12N 1522, C12N 516, A61K 3821

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057957797

ABSTRACT:
.beta.-interferon is produced in Chinese hamster ovary cells (CHO) in high amounts.

REFERENCES:
patent: 4399216 (1983-08-01), Axel et al.
patent: 4414150 (1983-11-01), Goeddel
patent: 4446235 (1984-05-01), Seeburg et al.
patent: 4518584 (1985-05-01), Mark et al.
patent: 4634665 (1987-01-01), Axel et al.
patent: 4656134 (1987-04-01), Ringold
patent: 4738931 (1988-04-01), Sugano et al.
patent: 4741901 (1988-05-01), Levinson et al.
patent: 4762791 (1988-08-01), Goeddel et al.
patent: 4766075 (1988-08-01), Goeddel et al.
patent: 4808523 (1989-02-01), Revel et al.
patent: 4966843 (1990-10-01), McCormick et al.
patent: 5004689 (1991-04-01), Fiers et al.
patent: 5010002 (1991-04-01), Levinson et al.
patent: 5015730 (1991-05-01), Friesen et al.
patent: 5112755 (1992-05-01), Heyneker et al.
patent: 5179017 (1993-01-01), Axel et al.
patent: 5468607 (1995-11-01), Revel et al.
patent: 5554513 (1996-09-01), Revel et al.
Colby et al., "Regulation of Expression of IFN Genes in Different Host Cells", The Third Annual International Congress for Interferon Research, Miami, FL, Nov. 1-3, 1982.
Friesen et al., "Purification and Molecular Characterization of . . . ", Arch. Biochem. Biophys., vol. 206(2), pp. 432-450, 1981.
Hauser et al., "Studies on the Regulation of the Human Interferon-.beta. Gene", The Second Annual International Congress for Interferon Research, Oct. 21-23, 1981.
Meager et al., "Somatic Cell Genetics of Human Interferon Production in Human-Rodent Cell Hybrids", J. Gen. Virol., vol. 45, pp. 309-321, 1979.
Morgan et al., "The Expression of the Interferon System in Clones of Chinese Hamster/Human Hybrid Cells", British J. Cancer, vol. 35, p. 254, 1977.
Pitha et al., "Analysis of .beta. Interferon mRNA in Eukaryotic Cells Induced to Produce Interferon", The Second Annual International Congress for Interferon Research, Oct. 21-23, 1981.
Reyes et al., "Expression of Human .beta.-Interferon linked to HSV-1 TK Promoter Sequences in Mouse Cells and Xenopus Oocytes", J. Cellular Biol., Abstract Suppl. 6, 11.sup.th Annual UCLA Symposia, Abstract 0955, 1982.
Slate et al., "Fibroblast Interferon In Man Is Coded By Two Loci On Separate Chromosomes", Cell, vol. 16, pp. 171-180, 1979.
Ullrich et al., "The Human Leukocyte Interferon Gene Family: Structure and Expressions in Mammalian Cells", The Tenth Annual ICN-UCLA Symposium, Abstract 1092, Feb. 8-Mar. 20, 1981.
Weissmann et al., "Structure and Expression of Human IFN-.alpha. Genes", Antiviral Research, The Biology of the Interferon System, Abstract 1, No. 1, p. 2, Mar. 1981.
Crespi et al., "Microcarrier Culture: Applications in Biologicals Production and Cell Biology," Biotech. & Bioeng., 23:2673-2689 (1981).
Taniguchi, T., et al (1980) Proc. Natl. Acad. Sci. USA 77: 5230-33.
Shepard et al. Nature (1981) 294:563-565.
Goeddel et al. Nucleic Acids Res. (1980) 8:4057-4074.
Billiau et al. Antimicrobial Agents (1979) 16:49-55.
Knight et al. Science (1980) 207:525-526.
U.S. application No. 06/368,773, Heynecker et al., filed Apr. 15, 1982.
Biotechnology Newsletter, Jan. 4, 1982.
Wigler et al., Proc. Natl. Acad. Sci. USA, vol. 77, 1980, pp. 3567-3570.
Wahl et al., J. Biol. Chem., vol. 254, 1979, pp. 8679-8689.
O'Hare et al., Proc. Natl. Acad. Sci. USA, vol. 78, 1981, p. 1527.
Hamer et al., Nature, vol. 281, 1979, p. 35.
Mulligan and Berg, Science, vol. 209, 1980, pp. 1422-1427.
Mulligan and Berg, PNAS USA, vol. 78, 1981, pp. 2072-2076.
Chasin and Urlaub, Banbury Rpt., Cold Spring Harbor, 1979, pp. 201-208.
Fiers et al., Phil. Trans. R. Soc. Lond B., vol. 299, 1982, pp. 29-38.
Gasser et al., Proc. Natl. Acad. Sci., vol. 79, 1982, pp. 6522-6526.
Haynes and Weissman, Nucleic Acid Res., vol. 11(3), 1983, pp. 687-706.
Christman et al., Proc. Natl. Acad. Sci. USA, vol. 79, 1982, pp. 1815-1819.
Derynck et al., in The Biology of the Interferon System, Proc. of the Intl. Meeting on the Biol. of the Interferon System, held in Rotterdam, The Netherlands on 21-24 Apr. 1981, ed. DeMaeyer et al., pp. 57-62.
Gross et al., in The Biology of the Interferon System, Proc. of the Intl. Meeting on the Biol. of the Interferon System, held in Rotterdam, The Netherlands on 21-24 Apr. 1981, ed. DeMaeyer et al., pp. 85-90.
Srinivasan et al., Intro. of Macromolecules in Viable Mammalian Cells, 1980, pp. 27-45.
Lewis et al., Somatic Cell Genetics, Vo.. 6(3), 1980, pp. 333-347.
Kaufman et al., J. Mol. Biol., vol. 159, 1982a, pp. 601-621.
Kaufman et al., Molecular and Cellular Biology, vol. 2(11), Nov. 3, 1982b, pp. 1304-1319.
Morgan, J. Gen. Virol., vol. 33, 1976, pp. 351-354.
Lee et al., Nature, vol. 294, Nov. 19, 1981, pp. 228-232.
Abraham et al., Somatic Cell Genetics, vol. 8(1), 1982, pp. 23-29.
Hajnicka et al., Interferon and Interferon Inducers Conf., Foldes et al. eds., Tihany, Hungary, Sep. 12-14, 1974.
R.J. Kaufman et al., "Expression and Amplification of DNA Introduced . . . " Gene Amplification, pp. 244-250, Mar. 1, 1982.
Alt et al., J. of Biol. Chem., vol. 253(5), Mar. 10, 1978, pp. 1357-1370.
Kaufman et al., J. of Biol. Chemistry, vol. 253(16), Aug. 25, 1978, pp. 5852-5860.
Kaufman et al., Proc. Natl. Acad. Sci. USA, vol. 76(11), Nov. 1979, pp. 5669-5673.
Kaufman et al., Mol. and Cellular Biol., Dec. 1981, pp. 1069-1076.
Nunberg et al., Proc. Natl. Acad. Sci. USA, vol. 75(11), Nov. 1978, pp. 5553-5556.
N. Mantei et al., Nature, vol. 297, 1982, pp. 128-132.
G. Ringold et al., J. Molec. Appl. Genetics, vol. 1, 1982, pp. 165-175.
Schimke, Sci. Am., vol. 243, Nov. 1980, p. 60.
Gorman et al., CA 92:193968f (1982) of Mol. Cell Biol., vol. 2, 1982, p. 1044.
Weiss, RNA Tumor Viruses, Cold Spring Harbor Lab., 1982, pp. 851-852.
Subramani et al., Mol. Cell. Biol., vol. 1, 1981, p. 854.
Cavalieri et al., "Induction and decay of human fibroblast . . . ", Proc. Natl. Acad. Sci. USA, 74(10):4415-4419, Oct. 1977.
Christman et al., "Amplification of expression of hepatitis B . . . ", Proc. Natl. Acad. Sci. USA, vol. 79, pp. 1815-1918, Mar. 1982.
Kohase and Vilcek, "Regulation of Human Interferon Production . . . ", Virology, vol. 76, pp. 47-54, 1977.
Jameson and Grossberg, "Production of Interferon in Human Cell . . . ", Human Interferon Production and Clinical Use, pp. 37-53, 1978.
Johnston, "Induction of Interferon in Human Lymphoblastoid . . . ", The Biology of Interferon System, pp. 35-38, 1981.
Kauppinen et al., "Large Scale Production and Properties of Human . . . ", Human Interferon Production and Clinical Use, pp. 1-13, 1978.
Martin J. Page, "Expression of amplified human beta interferon genes . . . ", Gene, vol. 37, pp. 139-144, 1985.
Rubinstein et al., "Human leukocyte interferon: Production, . . . ", Proc. Natl. Acad. Sci. USA, 76(2):640-644, Feb. 1979.
Wm. E. Stewart, II, "Varied Biologic Effects of Interferon", Interferon 1979: vol. I, pp. 29-51, 1979.
Vilcek et al., "Selection of New Human Foreskin Fibroblast Cell . . . ", Human Interferon Production and Clinical Use, pp. 101-118, 1978.
McCormick et al., "Inducible Expression of Amplified Human Beta . . . ", Molecular and Cellular Biology, 4(1):166-172, Jan. 1984.
Abstract, "Gene Expression" (No. 0338), J. of Cellular Biochem., 12th Annual UCLA Symposia, Alan R. Liss, Inc., New York, Jan. 30-Apr. 2, 1983.
Reiser and Hauser, Recombinant Human Interferon Beta from Mammalian Cells Lines, Arzneim-Forsch./Drug Res., 37(1):377-490, Apr. 1987.
Abstract, Chengzu et al., "Constitutive Production of HUFN-.beta. and High Density Cultivation of CHO Cells" (No. I1-10), J. of Interferon Research, 1990 Annual Mtg. of the ISIR, 14-18 Nov. 1990.
Konrad, "Applications of Genetic Engineering to the Pharmaceutical Industry", Biochemical Engineering III, vol. 413, pp. 12-22, 1983.
Chernajovsky et al., "Efficient Constitutive Production of Human Fibroblast Interferon by Hamster Cells Transformed with the IFN-.beta..sub.1 Gene Fused to An SV40 Early Promoter", DNA, vol. 3(4):297-308, 1984.
McCormick et al., "Inducible Expression of Amplified Human Beta Interferon Genes in CHO Cells", Molecular and Cellular Biology, vol. 4(1):166-172, Jan. 1984.
Bendig, "The production of foreign proteins in mammalian cells" in Genetic Engineering 7, edi

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