Human immunodeficiency virus immunogenic composition

Details Human immunodeficiency virus immunogenic composition Human immunodeficiency virus immunogenic composition

2006-01-03

2006-01-03

Stucker, Jeffrey (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fusion protein or fusion polypeptide

C424S188100, C424S208100, C514S002600

Reexamination Certificate

active

06982086

ABSTRACT:
The present invention relates to a method of immunizing a patient against human immunodeficiency virus (HIV) and to an HLA-based immunogenic composition suitable for use in such a method.

REFERENCES:
patent: 5013548 (1991-05-01), Haynes et al.
patent: 5019387 (1991-05-01), Haynes et al.
patent: 5030449 (1991-07-01), Berzofsky et al.
patent: 5081226 (1992-01-01), Berzofsky et al.
patent: 5336758 (1994-08-01), Berzofsky et al.
patent: 5352576 (1994-10-01), Haynes et al.
patent: 5516632 (1996-05-01), Palker et al.
patent: 5622703 (1997-04-01), Berzofsky et al.
patent: 5695762 (1997-12-01), Berzofsky et al.
patent: 5711947 (1998-01-01), Berzofsky et al.
patent: 5820865 (1998-10-01), Berzofsky et al.
patent: 5853978 (1998-12-01), Berman et al.
patent: 5864027 (1999-01-01), Berman
patent: 5882853 (1999-03-01), Berzofsky et al.
patent: 5932218 (1999-08-01), Berzofsky et al.
patent: 5939074 (1999-08-01), Berzofsky et al.
patent: 5976541 (1999-11-01), Berzofsky et al.
patent: 5976551 (1999-11-01), Mottez et al.
patent: 5980899 (1999-11-01), Berzofsky et al.
patent: 5993819 (1999-11-01), Haynes et al.
patent: 5997869 (1999-12-01), Goletz et al.
patent: 6042836 (2000-03-01), Berman et al.
patent: 6214347 (2001-04-01), Berzofsky et al.
patent: 6290963 (2001-09-01), Fischinger et al.
patent: 6294322 (2001-09-01), Berzofsky et al.
patent: 6458527 (2002-10-01), Luciw et al.
patent: 6592872 (2003-07-01), Klimpel et al.
patent: 6656471 (2003-12-01), Sastry et al.
patent: 2002/0086283 (2002-07-01), Haynes et al.
patent: 2003/0147888 (2003-08-01), Haynes et al.
patent: 2004/0001851 (2004-01-01), Haynes et al.
patent: 2004/0039172 (2004-02-01), Haynes et al.
patent: 2004/0086506 (2004-05-01), Haynes et al.
patent: 2004/0132010 (2004-07-01), Haynes et al.
patent: 2004/0197344 (2004-10-01), Haynes et al.
patent: 0 693 938 (1996-01-01), None
patent: WO 91/04051 (1991-04-01), None
patent: WO 93/04697 (1993-03-01), None
patent: WO 93/15750 (1993-08-01), None
patent: WO 94/26785 (1994-11-01), None
patent: WO 94/28929 (1994-12-01), None
patent: WO 94/29339 (1994-12-01), None
patent: WO 95/29700 (1995-11-01), None
patent: WO 96/41189 (1996-12-01), None
patent: WO 97/14436 (1997-04-01), None
patent: WO 98/01564 (1998-01-01), None
patent: WO 00/52040 (2000-09-01), None
patent: WO 01/43693 (2001-06-01), None
patent: WO 01/54719 (2001-08-01), None
patent: WO 01/56355 (2001-08-01), None
patent: WO 02/08716 (2002-01-01), None
patent: WO 02/20555 (2002-03-01), None
patent: WO 02/024149 (2002-03-01), None
patent: WO 2002/20554 (2002-03-01), None
patent: WO 02/069691 (2002-09-01), None
patent: WO 03/039470 (2003-05-01), None
patent: WO 03/046137 (2003-06-01), None
patent: WO 2004/009785 (2004-01-01), None
patent: WO 2004/075850 (2004-09-01), None
patent: WO 2005/016952 (2005-02-01), None
patent: WO 2005/028625 (2005-03-01), None
Riffkin et al. “A single amino-acid change between the antigenically different extracellular serine proteases V2 and B2 fromDichelobacter nodosus”, Gene, vol. 167 (1995), pp. 279-283.
Abaza et al. “Effects of amino acid substitutions outside and antigenic site on protein binding to monoclonal antibodies of predetermined specificity obtained by peptide immunization”,Journal of Protein Chemistry, vol. 11, No. 5 (1992), pp 433-444.
Cruse et al.Illustrated Dictionary of Immunology(Boca Raton, FL, CRC Press, Inc., 1995), p. 309. QR180.4.C78.
PaulFundamental Immunology, (Philadelphia & New York, Lippincott-Raven Publishers, 1993), pp. 250, 1311, 1312 QR181.F84.
Hale et al, “T Cell Multideterminant Regions in the Human Immunodeficiency Virus Envelope: Toward Overcoming the Problem of Major Histocompatibility Complex Restriction”, International Immunology 1(4):409-415 (1989).
Loktev et al, “Design of immunogens as components of a new generation of molecular vaccines”, Journal of Biotechnology 44(1):129-137 (1996).
Wain-Hobson, “Is Antigenic Variation of HIV Important for AIDS and What Might Be Expected in the Future?”, The Evolutionary Biology of Viruses. Stephen S. Morse (ed), Raven Press, Ltd., New York, pp. 185-209 (1994).
Sheppard et al, “The characterization of non-progressors: long-term HIV-1 infection will stable CD4+ T-cell levels”, AIDS 7:1159-1166 (1993).
Phair, John P., Keynote Address: “Variations in the Natural History of HIV Infection”, AIDS Research and Human Retroviruses 10(8):883 885 (1994).
Pantaleo et al, “Studies in Subjects with Long-Term Nonprogressive Human Immunudeficiency Virus Infection”, N. Engl. J. Med. 332(4):209-216 (1995).
Cao et al, “Virologic and Immunologic Characterization of Long-Term Survivors of Human Immunodeficiency Virus Type I Infection”. N. Engl. J. Med. 332(4):201-208 (1995).
Pantaleo et al., “Major expansion of CD8+ T cells with a predominant Vβ usage during the primary Immune response to HIV”. Nature 3970:463-467 (1994).
Mellors et al. “Quantitation of HIV-1 RNA in Plasma Predicts Outcome after Seroconversion”, Ann. Intern. Med. 122:573-579 (1995).
Jurriaans et al, “The Natural History of HIV-1 Infection: Virus Load and Virus Phenotype Independent Determinants of Clinical Course?”, Virology 204:223-233 (1994).
Borrow et al, “Virus-Specific CD8+ Cytotoxic T-Lymphocyte Activity Associated with Control of Viremia in Primary Human Immunodeficiency Virus Type I Infection”, Journal of Virology 68(9):6103-6110 (1994).
Haynes et al. “Toward an Understanding of the Correlates of Protective Immunity to HIV Infection”, Science 271:324-328 (1996).
Haynes, Barton F., “Scientific and Social Issues of Human Immunodeficiency Virus Vaccine Development”, Science 260:1279-1286 (1993).
Nowak et al. “Antigenic oscillations and shifting Immunodominance in HIV-1 Infections”, Nature 375:606-611 (1995).
Walker et al, “CD8+ Lymphocytes Can Control HIV Infection in Vitro by Suppressing Virus Replication”, Science 234:1563-1566 (1986).
Baler et al, “HIV suppression by interleukin-16”, Nature 378:563 (1995).
Cocchi et al, “Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8+ T Cells ”. Science 270:1811-1815 (1995).
Feng et al, “HIV-1 Entry Cofactor” Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor, Science 272:872-877 (1996).
Wei et al, “Viral dynamics in human immunodeficiency virus type I infection”, 373:117-122 (1995).
Palker et al. “Polyvalent Human Immunodeficiency Virus Synthetic Immunogen Comprised of Envelope gp120 T Helper Cell Sites and B Cell Neutralization Epitopes”. The Journal of Immunology 142:3612-3619 (1989).
Berzofsky, Jay A., “Development of artificial vaccines against HIV using defined epitopes”, The FASEB Journal 5:2412-2418 (1991).
Haynes et al, “HIV Type I V3 Region Primer-Induced Antibody Suppression Is Overcome by Administration of C4-V3 Peptides as a Polyvalent Immunogen”, AIDS Research and Human Retroviruses 11(2):211-221 (1995).
Williams and McAuley, “HLA Class I Variation Controlled for Genetic Admixture in the Gila River Indian Community of Arizona: A Model for the Paleo-Indians”, Human Immunology 33:39-46 (1992).
Hardy, G.H., “Mendelian Proportions in a Mixed Population”, Science, N.S. XXVII,(706):49-50 (1908).
Schneider et al, “Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara”, Nature Medicine 4:397-402 (1998).
Ferrari et al, “Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers”, Proc. Natl. Acad. Sci. USA 94:1396-1401 (1997).
Cease and Berzofsky, “Toward A Vaccine For AIDS: The Emergence of Immunobiology-Based Vaccine Development”, Annu. Rev. Immunol. 12:923-989 (1994).
Guleria et al,

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