Human immunodeficiency virus (hiv) env-coded peptide capable of

Details Human immunodeficiency virus (hiv) env-coded peptide capable of Human immunodeficiency virus (hiv) env-coded peptide capable of

1989-03-20

1996-10-08

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

4242081, 530324, 530325, 530326, 530327, A61K 3921, A61K 3800, C07K 500, C07K 700

Patent

active

055629059

ABSTRACT:
A chemically synthesized 15 amino acid peptide designated peptide 1-69, which has the sequence of amino acids numbers 308 to 322 (RIQRGPGRAFVTIGK) of the human immunodeficiency virus-1 (HIV-1) IIIB env-coded protein, was used to immunize animals. Peptide 1-69 elicited in immunized animals antibodies that block HIV proliferation and block HIV-induced cell fusion in cell culture.

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