Human immune system in non-human animal

Multicellular living organisms and unmodified parts thereof and – Nonhuman animal

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800DIG2, 800DIG5, 424 9371, 424 937, 424 931, 424 91, 424534, 424577, 424578, 435325, A61K 3500, A61K 4800, C12N 1500

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056987676

ABSTRACT:
Laboratory non-human animals in which the immune system of a donor is induced in and thrives in vivo and expresses the immune response of the donor animal in a recipient non-human animal of a different species than the donor, and wherein malignant immune system cells of the donor can be induced in the recipient non-human animal by injection of non-malignant donor into the recipient are disclosed.

REFERENCES:
patent: 4624917 (1986-11-01), Sugimoto
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