Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1985-09-11
1988-02-23
Martinell, James
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 60, 435 70, 435 71, 435 91, 4351721, 4351723, 4352402, 435243, 435253, 435811, 4353171, 435320, 935 11, 530351, C07H 2102, C12P 2100, C12P 2102, C12P 2104, C12P 1934, C12N 120, C12N 1500, C12N 500, C12N 100, C07K 1300
Patent
active
047271388
ABSTRACT:
Disclosed is a complete description of the preparation of novel, substantially pure polypeptide via recombinant DNA techniques utilizing any of an assortment of expression vectors and host cultures. The polypeptide, human immune (gamma) interferon (IFN-.gamma.), is isolated and characterized in terms of DNA and amino acid sequences, physical attributes and biological activity.
REFERENCES:
patent: 4332892 (1982-06-01), Ptashne et al.
patent: 4338397 (1982-07-01), Gilbert et al.
Gene Expression, vol. 2, Eucaryotic Chromosomes, Lewin, 1974, John Wiley & Sons, New York, pp. 148-156.
de Ley, M. et al., Eur. J. Immunol., 10: 877 (1980).
Yip, Y. K. et al.; Proc. Nat. Acad. Sci. (U.S.A.) 78: 1601 (1981).
Berger, S. L. et al., J. Biol. Chem., 225: 2955 (1980).
Botstein et al.; Recomb. DNA Tech. Bull. 2, 49 (1979).
Dianzani et al.; Nature 283, 400 (1980).
Wallace et al.; Fed.Proc. 40, 1574 (1981).
Wallace et al.; Biochem. Biophys. Res. Commun. 100, 865 (1981).
Taniguchi et al.; Proc. Natl. Acad. Sci. U.S.A. 78, 3469 (1981).
Epstein, L. B., Fed. Proc., 40, 56 (1981).
Vilcek, J. et al.; Microbiol., 204-207 (1980).
Novokhatskii et al.; Chem. Abstr. 96, 120770e (1982) first pub. in Dokl. Akad. Nauk SSSR, 261 997 (1981).
Goeddel et al.; Nature 287, 411 (1980).
Hamer et al.; Nature 281, 35 (1979).
Weissman, in Interferon 1981, vol. 3, Gresser (ed.), Academic Press, 1981, pp. 101-134.
Vilcek, in Interferon 1982, vol. 4, Academic Press, 1982, pp. 129-154.
Murray, Annals of Internal Medicine, 98, 1016 (1983).
Life, May 1980, pp. 50-54.
Time, Mar. 31, 1980, pp. 60-66.
Devos et al. Nucl. Acids Res. 10, 2487 (1982).
Epstein, Nature 295, 453 (1982).
Epstein, in Interferon 1981, Vo. 3, Gresser (ed.), Academic Press, 1981, pp. 13-44.
Nathan et al., Nature 292, 842-844 (1981).
Yip et al., Science 215, 411 (1982).
Genetic Engineering Letter, vol. 2, No. 17, "Artificial Gene for Gamma Interferon Reported by Japanese Scientist" (1982).
Newmark, Nature 294, 7 (1981).
Goeddel David V.
Gray Patrick
Genentech Inc.
Martinell James
LandOfFree
Human immune interferon does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Human immune interferon, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human immune interferon will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-603491