Human IL-2 receptor .gamma.-chain molecule antibody

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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Details

5303891, 5303913, 435 71, 4241441, C07K 1628, C07K 14715, G01N 33566, A61K 39395

Patent

active

058891609

ABSTRACT:
The present invention relates to an IL-2 receptor .gamma. chain molecule, a DNA-sequence encoding the IL-2 receptor .gamma. chain molecule, a vector possessing said DNA-sequence, a cell transformed with said vector, a method for the production of an IL-2 receptor .gamma. chain molecule by culturing of said cell, an immune response regulatory agent comprising an IL-2 receptor .gamma. chain molecule and an antibody to an IL-2 receptor .gamma. chain molecule.

REFERENCES:
patent: 5582826 (1996-12-01), Shimamura et al.
Sugamura et al., The IL-2/IL-2 receptor system: involvement of a novel receptor subunit, gamma chain, in growth signal transduction, Tohoku J. Exp. Med., 168(2):231-7, 1992.
Sugamura et al., IL-2-induced signal transduction: Involvement of tyrosine kinase and IL-2 receptor gamma chain, Lymphokine Res., 9(4): 539-542, 1990.
Takeshita et al., An associated molecule, p64, with high-affinity interleukin 2 receptor, Int. Immunol., 2(5): 477-480, 1990.
Takeshita et al., Cloning of the gamma chain of the human IL-2 receptor, Science, 257: 379-382, Jul. 1992.

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