Human hybridroma fusion partner for production of human monoclon

Details Human hybridroma fusion partner for production of human monoclon Human hybridroma fusion partner for production of human monoclon

1984-11-20

1987-09-15

Tarcza, John Edward

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

43524027, 435948, 935 93, 935100, 935106, C12N 1500, C12N 500, C12R 191

Patent

active

046939750

ABSTRACT:
Somatic cell hybrids of purely human origin are described that are suitable fusion partners for producing hybridomas by fusion with antibody producing cells, which hybridomas are stable and continuous.

REFERENCES:
patent: 4529694 (1985-07-01), Lazarus et al.
patent: 4574116 (1986-03-01), Kaplan et al.
Pickering et al., "A Human Myeloma Cell Line that does not Express Immunoglobulin but Yields a High Frequency of Hybridomas", Journal of Immunology 129(1), pp. 406-412, (1982).
Littman et al., "Production of Human B-Cell Hybridomas from Patients with SLE", Arth. Rheum. 25(4), p. S28, (1982), Supp.
Shulman et al., "A Better Cell Line for Making Hybridomas Secreting Specific Antibodies", Nature 276, pp. 269-270, (1978).
Matsuoka et al., (1967), Proceedings of the Society for Experimental Biology and Medicine, 125: 1246-1250.
Kozbor et al., (1982), Proceedings of the National Academy of Sciences U.S.A., 79: 6651-6655.
Teng et al., (1983), Proceedings of the National Academy of Sciences U.S.A., 80: 7308-7312.
Milstein and Cuello, (1983), Nature, 305: 537-540.

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