Human herpesvirus type 8 isolated from human lymphoma cell line

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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4242041, 435 5, 4352351, 435238, A61K 39245, A61K 3912, C12N 700

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active

061499188

ABSTRACT:
A human lymphoma cell line containing a human herpesvirus type 8 (HHV-8) capable of in vitro growth and which produces HHV-8 virus particles upon induction of lytic viral growth is provided. Virus produced by the cell line of the invention is useful for the production of antibodies to an HHV-8 virus particle, viral protein, or viral peptide. Methods of screening a biological sample for the presence of HHV-8 virus particles, viral protein, or viral peptide from a human suspected of being infected with HHV-8 are provided as are methods of screening a biological sample of the human for antibodies to HHV-8.

REFERENCES:
patent: 5830759 (1998-11-01), Chang et al.
Boshoff et al., Lancet, 345 : 1043-1045, Apr. 22, 1995.
Biesinger et al., PNAS USA, 89: 3116-3119, Apr. 1992.
Flemington et al., J. Virol., 64(9): 4549-4552, Sep. 1990.
Cesarman, Ethel. et al., "Kaposi's Sarcoma--Associated Herpesvirus-like DNA Sequences in AIDS-Related Body-Cavity-Based Lymphomas", (May 4, 1995), N. Engl. J. Med., vol. 332, No. 18 pp. 1186-1191.
Chang, Yuan, et al., "Identification of Herpesvirus-Like DNA Sequences in AIDS-Associated Koposi's Sarcoma", (Dec. 16, 1994), Science, vol. 266, pp. 1865-1869.
Chadburn, Amy, et al., "CD30 (Ki-1) Positive Anaplastic Large Cell Lymphomas in Individuals Infected with the Human Immunodeficiency Virus", (Nov. 15, 1993) Cancer, vol. 72, No. 10, pp. 3078-3090.
Dambaugh, Timothy, et al., "Epstein-Barr virus (B95-8) DNA VII: Molecular cloning and detailed mapping", (May 1980) Proc. Natl. Acad. Sci. (USA), vol. 77, No. 5, pp. 2999-3003.
Green, I., et al., "Primary Lymphomatous Effusions in AIDS: A Morphological, Immunophenotypic, and Molecular Study", (1995) Modern Pathol., vol. 8, No. 1, pp. 39-45.
Herndier, Brian G., et al., "Acquired Immunodeficiency Syndrome-Associated T-Cell Lymphoma: Evidence for Human Immunodeficiency Virus Type 1-Associated T-Cell Transformation" (Apr. 1, 1992) Blood, vol. 79, No. 7, pp. 1768-1774.
Knowles, Daniel M., et al., "Molecular Genetic Analysis of Three AIDS-Associated Neoplasms of Uncertain Lineage Demonstrates Their B-Cell Derivation and the Possible Pathogenetic Role of the Epstein-Barr Virus", (Feb. 15, 1989) Blood, vol. 73, No. 3, pp. 792-799.
Moore, Patrick S., et al., "Detection of Herpesvirus-like DNA Sequences in Kaposi's Sarcoma in Patients with and Those Without HIV Infection", (May 4, 1995), N. Engl. J. Med., vol. 332, No. 18, pp. 1181-1185.
Ng, Valerie, L., "IgMs Produced by Two Acquired Immune Deficiency Syndrome Lymphoma Cell LInes: Ig Binding Specificity and V.sub.H -Gene Putative Somatic Mutation Analysis", (Feb. 15, 1994), Blood, vol. 83, No. 4, pp. 1067-1078.
Ng. Valerie, L., Erratum to: ["IgMs Produced by Two Acquired Immune Deficiency Syndrome Lymphoma Cell LInes: Ig Binding Specificity and V.sub.H -Gene Putative Somatic Mutation Analysis", (Feb. 15, 1994, Blood, vol. 83, No. 4, pp. 1067-1078], (Aug. 1, 1994), Blood, vol. 84, No. 3, p. 995.
Walts, Ann E., et al., "Diagnosis of Malignant Lymphoma in Effusions from Patients with AIDS by Gene Rearrangement", (Aug. 1990) A. J. Clin. Pathol. vol. 94, No. 2: pp. 170-175.

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