Human herpesvirus type 6 protein p100, the corresponding DNA seq

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 691, 435 701, 435 703, 435 711, 435 712, 4351723, 435243, 4352542, 43525421, 4353201, 435325, 435410, 435822, 435849, 435942, 536 2342, 935 23, 935 24, 935 52, 935 66, C07H 2104, C12N 1509, C12N 1538, C12P 2100

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058144757

ABSTRACT:
The invention relates to the human herpesvirus type 6 protein p100 and parts thereof having its specific immunological properties. It further relates to antibodies directed to them and to the corresponding DNA sequences. They can be used in pharmaceutical or diagnostic compositions, optionally together with other HHV-6 proteins or the corresponding DNA sequences.

REFERENCES:
Josephs et al., "Genomic Analysis Of The Human B-Lymphotropic Virus (HBLV)," Science, vol. 234, pp. 601-603 (Oct. 31, 1986).
Neipel et al., "Gene For The Major Antigenic Structural Protein (p100) Of Human Herpesvirus 6," The Journal Of Virology, vol. 66, No. 6, pp. 3918-3924 (Jun. 1992).
Identification, Cloning, and Expression of the Major Capsid Protein Gene of Human Herpesvirus 6, E. Littler et al., Journal of Virology, vol. 64, No. 2 Feb. 1990, pp. 714-722.
Serological Crossreaction of Human Herpesvirus 6 with Cytomegalovirus, C. Larcher et al., The Lancet, Oct. 22, 1988, pp. 963-964.
The Unique Region of the Human Herpesvirus 6 Genome is Essentially Collinear With the UL Segment of Human Cytomegalovirus, F. Neipel et al., Journal of General Virology (1991), 72, pp. 2293-2297.
Identification of a Nucleocapsid Protein as a Specific Serological Marker of Human Herpesvirus 6 Infection, M. Yamamoto et al., Journal of Clinical Microbiology, vol. 28, No. 9, Sep. 199, pp. 1957-1962.
Identification, Characterization, and Sequence Analysis of a cDNA Encoding a Phosphoprotein of Human Herpesvirus 6, C.K. Chang et al., Journal of Virology, vol. 65, No. 6, Jun. 1991, pp. 2884-2894.
Human Herpesvirus 6 Is Closely Related to Human Cytomegalovirus, G.L. Lawrence et al., Journal of Virology, vol. 64, No. 1, Jan. 1990, pp. 287-299.

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