Human herpesvirus-6 (HHV-6) isolation and products

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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435 5, C07K 1403

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active

060180277

ABSTRACT:
A new human B lymphotropic virus, also designated human herpesvirus-6, has been isolated. DNA, molecular clones, antigenic viral proteins and antibodies having specificity to the new virus have been prepared. Various utilities of the new virus and products derived therefrom have been described.

REFERENCES:
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patent: 5230997 (1993-07-01), Frenkel
Albashi et al., "HBLV (or HHV-6) in human cell lines)", Nature vol. 329, No. 6136 (Sep. 1987) p. 1723.
Lusso et al., "In vitro Cellular Tropism of Human B-Lymphotropic Virus . . . ", J. Exp Med. vol. 167 (May 1988) pp. 1659-1670.
Rodriquez et al., Recombinant DNA Techniques: An Introduction, (published 1983), pp. 74-76.
Josephs et al., "Genomic analysis of the human B-Lymphotropic virus", Science, vol. 24, pp. 601-603 (1986).
Lawrence et al., Human Herpesvirus 6 Is Closely Related to Human Cytomegalovirus. J. Virol. 64(1):287-299, 1990.
Frankel-Conrat et al., Virology, Prentice-Hall, Englewood, N.J., 1982, pp. 207-211.
Barnes, "Mystery Disease At Lake Tahoe Challenges Virologists and Clinicans", Science 234:542, 1986.

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