Human hepatoma-derived cell line FLC-4 and method for producing

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se

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435366, 435 703, 435 701, C12N 508, C12P 2104

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active

058044418

ABSTRACT:
Human hepatoma-derived cell line FLC-4 (deposited with the National Institute of Bioscience and Human-Technology, the Agency of Industrial Science and Technology under Accession Number FERM BP-5165), as well as a method for large-scale production of albumin by culturing the cell line with a radial-flow type bioreactor are provided.

REFERENCES:
S. Nagamori et al., "Information on Cell Lines", Human Cell, vol. 1, No. 1, Mar. (1988), (English translation).
S. Hasamura et al., Establishment and Characterization of a Human Hepatocellular Carcinoma Cell Line JHH-4, Human Cell, vol. 1, No. 1, (1988), pp. 98-100.
S. Nagamori., "Protein Secretion of Human Cultured Liver Cells", Human Cell, vol. 1, No. 4, (1988), pp. 382-390.
S. Homma et al., "Establishment and Characterization of a Human Hepatocellular Carcinoma Cell Line JHH-7 Producing .alpha.-Fetoprotein and Carcinoembryonic Antigen", Human Cell, vol. 3, No. 2, (1990), pp. 152-157.
M. Kawada et al., "New Liver Support System Composed of Functional Human Cells and a Radial-Flow Bioreactor", Human Cell, vol. 7, No. 2, (1990), pp. 95-100.
Matsuura et al, Acta. Med. Okayama, vol. 37, pp. 341-352 (1983).
Li et al, J. China Med Univ., 17(4) 1988, pp. 259-263.
Saint Ruf, et al, Oncogene, 7(8) 1992, pp. 1557-1565.
Wuu et al, Cancer Genet. Cytogenet., 26:279-286 (1987).

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