Human H37 proteins and cDNA encoding the same

Details Human H37 proteins and cDNA encoding the same Human H37 proteins and cDNA encoding the same

2005-05-24

2005-05-24

Nickol, Gary (Department: 1642)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

C530S388240, C530S389200, C530S350000, C530S358000, C536S023100, C536S024300

Reexamination Certificate

active

06897054

ABSTRACT:
This application provides human H37 protein having an amino acid sequence of SEQ ID NO: 1 or NO: 2; human gene encoding the protein; cDNA of the human gene which has a base sequence of SEQ ID NO: 3 or NO: 4; DNA fragment comprising a partial sequence of the cDNA; recombinant vector having the cDNA; antibody against human H37 protein; and a method for controlling the proliferation of cells by introducing the above DNA or antibody into the cells.

REFERENCES:
patent: WO200058473 (2000-10-01), None
patent: WO200157278 (2001-08-01), None
Kumagai H, Sato N, Yamada M, Mahony D, Seghezzi W, Lees E, Arai K, Masai H. A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells. Mol Cell Biol. Jul. 1999;19(7).*
Molecular and Cellular Biology, vol. 19, No. 7, issued Jul. 1999, Hiroyuki Kumagai et al., “A Novel Growth- and Cell Cycle- Regulated Protein, ASK, Activates Human Cdc7-Related Kinase and is Essential for G1/S Transition Mammalian Cells”, pp. 5083-5095.
Database MEDLINE on PubMed, Accession No. 10523313, Jiang, W. et al., “Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication”, EMBO Journal, vol. 18, No. 20, issued 15 Oct. 1999, pp. 5703-5713.
Database GenBank, Accession No. AF160876, Jul. 22, 1999, Hollingsworth, R., “Homo sapiens DBF4-like protein (DBF4) mRNA, complete cds.”.
The Journal of Biological Chemistry, vol. 273, No. 36, issued Sep. 4, 1998, Jung Min Kim et al., “Growth Regulation of the Expression of Mouse cDNA and Gene Encoding a Serine/Threonine Kinase Related to Saccharomyces cerevisiae CDC7 Essential for G1/S Transition”, pp. 23248-23257.
Proceedings of the National Academy of Sciences, USA, vol. 94, No. 26, issued Dec. 23, 1997, Wei Jiang et al., “Identification and Characterization of a human protein kinase related to budding yeast Cdc7p”, pp. 14320-14325.
The EMBO Journal, vol. 16, No. 14, issued Jul. 16, 1997, Noriko Sato et al., “Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7”, pp. 4340-4351.

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