Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-02-24
2000-10-24
Ulm, John
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435243, 4353201, 435325, 530399, 530402, 536 2351, 930120, C12N 1518, C12N 1563, C07K 1461
Patent
active
061365637
ABSTRACT:
Human growth hormone variants are disclosed having enhanced affinity for the growth hormone receptor. Also disclosed are human growth hormone variants conjugated to one or more chemical groups, such as poly(ethylene glycol), which is believed to prolong the in vivo half-life of the variants.
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Kr
Clark Ross G.
Cunningham Brian C.
Fuh Germaine G.
Olson Kenneth
Wells James A.
Genentech Inc.
Saoud Christine
Ulm John
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