Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1998-12-18
2000-11-21
Moezie, F. T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 2, 514 8, 530324, 530351, 530380, 530395, 530397, 530399, 530829, 435 691, A61K 3827
Patent
active
061503312
ABSTRACT:
Provided is an aqueous pharmaceutical composition comprising human growth hormone wherein said human growth hormone is dissolved in a benzalkonium chloride-containing, slightly to weakly acidic solution buffered, most preferably, with maleate. The composition is sufficiently stable to be supplied in liquid state and can be prepared as a less painful composition.
REFERENCES:
patent: 5763394 (1998-06-01), O'Connor et al.
Becker et al., Biotechnology and Applied Biochemistry, vol. 9, pp. 478-487 (1987).
Becker et al., Biotechnology and Applied Biochemistry, vol. 10, pp. 326-337 (1988).
Inoue Katsura
Kajihara Jun-ichi
Tatsumi Masafumi
JCR Pharmaceuticals Co. Ltd.
Moezie F. T.
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