Human glycosyltransferase gene, compounds and method for inhibit

Details Human glycosyltransferase gene, compounds and method for inhibit Human glycosyltransferase gene, compounds and method for inhibit

1997-11-20

1999-03-02

Wax, Robert A.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Transferases

435193, 4352523, 43525233, 4353201, 536 232, 536 235, A61K 3845, C12N 910

Patent

active

058767142

ABSTRACT:
A gene encoding human glycosyltransferase (human GnT-III) and recombinant DNA method for producing the enzyme are provided. A cancerous metastasis inhibitor comprising GnT-III, or a gene thereof, and a method of inhibiting cancerous metastasis in a mammal are also provided.

REFERENCES:
Y. Ihara et al., J. Biochem., 113(6), 692-698 (Jun. 1993).
A. Nishikawa et al., J. Biol. Chem., 267(25), 18199-18204 (Sep. 1992).
H. Nakao et al., Biochem. Biophys. Res. Commun., 172(3), 1260-1266 (Nov. 15, 1990).
K. Ishibashi et al., Clin. Chim. Acta., 185(3), 325-322 (Dec. 15, 1989).
A. Nishikawa et al., Anal. Biochem., 170(2), 349-354 (1988).

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