Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1987-12-03
1989-05-30
Hazel, Blondel
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
435 68, 435811, 424 855, C07K 1300, C07K 1526, A61K 4502, C12P 2100
Patent
active
048352560
ABSTRACT:
Disclosed is a novel DNA which shows complementarity to human interferon-.gamma. mRNA, a recombinant plasmid containing the DNA, a microorganism containing the recombinant plasmid and a method of producing the same as well as a process for producing a polypeptide having human interferon.gamma. activity using the microorganism.
REFERENCES:
Gray et al., Nature, vol. 295, pp. 503-508, 1982.
Rubins et al., Proc. Natl. Acad. Sci., vol. 77, pp. 5928-5932, 1980.
Lep et al., Proc. Natl. Acad. Sci., vol. 78, pp. 1601, 1605, 1981.
Taniguchi et al., Proc. Natl. Acad. Sci., vol. 78, pp. 3469-3472, 1981.
Chemical Abstracts, vol. 97, Abstract No. 18357v, 1982.
Chemical Abstracts, vol. 93, Abstract No. 130300d, 1980.
Nishi Tatsunari
Sugano Haruo
Taniguchi Tadatsugu
Vilcek Jan T.
Yip Yum K.
Hazel Blondel
Japanese Foundation for Cancer Research
New York University & Juridical Foundation
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