Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1992-10-09
1999-12-14
Horlick, Kenneth R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 691, 4353201, 4352523, C12Q 168, C07H 2109
Patent
active
060015608
ABSTRACT:
Stably-transformed human cell lines containing a human gamma interferon-responsive human HLA-DR.alpha. promoter operatively linked to a reporter gene are provided. Also provided are methods for using such transformed cell lines to screen for agonists and/or antagonists of human gamma interferon.
REFERENCES:
patent: 4727138 (1988-02-01), Goeddel et al.
patent: 5223421 (1993-06-01), Smith et al.
Wurm et al. Biologicals 18:159-164 (1990).
MacDonald Critical Reviews in Biotechnology 10(2):155-178 (1990).
(4AR) Tsang et al. Mol. & Cell Biol. 10(2):711 (1990).
(3AT) Tsang et al. P.N.A.S. 85:8598 (1988).
Selden et al. Mol. and Cell Biol. 6(9):3173 (1986).
Blanai et al. P.N.A.S. 85:4672 (1988).
Sugimoto et al. Cancer Res. 49:1824 (1989).
Koeffler et al. P.N.A.S. 81:4080 (1984).
Rosa et al. J. of Immunol.140(5):1660 (1988).
Basta et al., J. Immunol. 138:1275 (1987).
Basta et al., Proc. Natl. Acad. Sci. USA 85:8618 (1988).
Das et al., Proc. Natl. Acad. Sci. USA 80:3543 (1983).
Dorn et al., Proc. Natl. Acad. Sci. USA 84:6249 (1987).
Miwa et al., Proc. Natl. Acad. Sci. USA 84:4939 (1987).
Selden et al., Mol. Cell Biol. 6:3173 (1986).
Sherman et al., Proc. Natl. Acad. Sci. USA 84:4254 (1987).
Sherman et al., Mol. Cell. Biol. 9:50 (1989).
Tsang et al., Proc. Natl. Acad. Sci. USA 85:8598 (1988).
Tsang et al., Mol. Cell. Biol. 10:711 (1990).
Lonial Herinder K.
Narula Satwant K.
Zavodny Paul J.
Horlick Kenneth R.
Schering Corporation
Thampoe Immac J.
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