Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-01-23
1998-11-17
Feisee, Lila
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4391723, 4393201, 4392523, 439325, 439348, 439371, 536 231, 536 235, C12N 1500, C12N 120, C12P 2102, C07H 2104
Patent
active
058374930
ABSTRACT:
The present invention provides two novel human galectins (designated individually as GAL-5HA and GAL-5HB, and collectively as GAL-5H) and polynucleotides which identify and encode GAL-5H. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding GAL-5H and a method for producing GAL-5H. The invention also provides for use of GAL-5H and agonists, antibodies, or antagonists specifically binding GAL-5H, in the prevention and treatment of diseases associated with expression of GAL-5H. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding GAL-5H for the treatment of diseases associated with the expression of GAL-5H. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding GAL-5H.
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Bandman Olga
Goli Surya K.
Hawkins Phillip R.
Hillman Jennifer L.
Petithory Joanne R.
Billings Lucy J.
Feisee Lila
Incyte Pharmaceuticals Inc.
Sun-Hoffman Lin
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