Human galactokinase gene

Details Human galactokinase gene Human galactokinase gene

1995-05-26

1998-11-03

Chambers, Jasemine C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 691, 435 9141, C12Q 168, C07H 2100, C12N 1512, C12N 1555

Patent

active

058306498

ABSTRACT:
This invention relates to human galactokinase and the identification of galactokinase mutations, a missense and nonsense, as well as isolated nucleic acids encoding same, recombinant host cell transformed with DNA encoding such proteins and to uses of the expressed proteins and nucleic acid sequences in therapeutic and diagnostic applications.

REFERENCES:
Stambolian, et al., "Purification of Human Galactokinase and Evidence For Its Existence as a Monomer Form", (1985), Biochimica Biophysica Acta, 831:306-312.
Lee et al., "Cloning of a Human Galactokinase Gene (GK2) on Chromosome 15 By Complementation in Yeast", (1992), Proc. Natl. Acad. Sci, USA, 89:10887-10891.
Debouck, et al., "Structure of the Galactokinase Gene of Escherichia coli, the Last (?) Gene of the gal Operon", (1985), Nucl. Acids Research, 13:1841-1853.
Glaser, et al., "Bacillus subtilis Genome Project: Cloning and Sequencing of the 97 kb Region From 325.degree. to 333.degree.", (1993), Molecular Microbiology, 10:371-384.
Houng, et al., "Molecular Cloning and Physical and Functional Characterization of the Salmonella typhimurium and Salmonella typhi Galactose Utilization Operons", (1990), Journal of Bacteriology, 172:4392-4398.

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