Human GABA B receptor 1 promoters

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Reexamination Certificate

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C435S252300, C435S320100, C435S325000, C435S471000, C536S023100

Reexamination Certificate

active

07348163

ABSTRACT:
The present invention relates to nucleic acid molecules constituting GABABreceptor 1 promoters P1a and/or P1b, and to methods for screening for compounds which are modulators of GABABreceptor 1 transcription, said methods comprising the use of nucleic acid molecules constituting GABABreceptor P1a and/or P1b promoters.

REFERENCES:
patent: WO 97/46675 (1997-12-01), None
patent: WO 99/21890 (1999-05-01), None
Mu W and Burt DR. Molecular Brain Research 73:172-180, 1999.
Peters, H.C. et al.,Mapping, genomic structure, and polymorphisms of the human GABABR1 receptor gene: evaluation of its involvement in idiopathic generalized epilepsy, Neurogenetics, vol. 2, pp. 47-54 (1998).
Younger, R., EMBL Database/Genbank/DBJ, Accession No. AL031983, “Direct Submission” (submitted Jan. 20, 1999).

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