Human G-protein coupled receptor polynucleotides

Details Human G-protein coupled receptor polynucleotides Human G-protein coupled receptor polynucleotides

1997-10-28

2000-04-11

Teng, Sally

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

536 235, 4352523, 43525411, 4353201, 435325, C12N 1509, C07K 14705

Patent

active

060487119

ABSTRACT:
A novel G-protein coupled receptor protein, a partial peptide and their salts are disclosed. DNA encoding the receptor protein, production of the receptor protein, determination of a ligand to the receptor protein, a method for screening for compounds which inhibit ligand binding to the receptor protein, a kit for screening for such compounds are also disclosed. The receptor protein, its partial peptide and their salts are used for screening for candidate compounds of drugs and the like.

REFERENCES:
Z. Zeng, et al., "A Novel Endothelin Receptor Type-B-like Gene Enriched in the Brain ", Biochemical and Biophysical Research Communications, 233:559-567 (1997).

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