Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2008-07-01
2008-07-01
Ulm, John (Department: 1649)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C424S144100, C435S334000, C536S023530
Reexamination Certificate
active
10994679
ABSTRACT:
The present invention relates to a novel human protein called Human G-protein Chemokine Receptor (CCR5) HDGNR10, and isolated polynucleotides encoding this protein. The invention is also directed to human antibodies that bind Human G-protein Chemokine Receptor (CCR5) HDGNR10 and to polynucleotides encoding those antibodies. Also provided are vectors, host cells, antibodies, and recombinant methods for producing Human G-protein Chemokine Receptor (CCR5) HDGNR10 and human anti-Human G-protein Chemokine Receptor (CCR5) HDGNR10 antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to this novel human protein and these novel human antibodies.
REFERENCES:
patent: 5314992 (1994-05-01), Guyre et al.
patent: 5440021 (1995-08-01), Chuntharapai et al.
patent: 5652133 (1997-07-01), Murphy
patent: 5707815 (1998-01-01), Charo et al.
patent: 5776729 (1998-07-01), Soppet et al.
patent: 5798206 (1998-08-01), Neurath et al.
patent: 5817310 (1998-10-01), Ramakrishnan et al.
patent: 5912176 (1999-06-01), Wang
patent: 5919776 (1999-07-01), Hagmann et al.
patent: 5928881 (1999-07-01), Barnette et al.
patent: 5939320 (1999-08-01), Littman et al.
patent: 5939538 (1999-08-01), Leavitt et al.
patent: 5961976 (1999-10-01), Wang
patent: 5962462 (1999-10-01), Mills et al.
patent: 5994515 (1999-11-01), Hoxie
patent: 6013644 (2000-01-01), Mills et al.
patent: 6025154 (2000-02-01), Li et al.
patent: 6057102 (2000-05-01), Landau et al.
patent: 6075181 (2000-06-01), Kucherlapati et al.
patent: 6107019 (2000-08-01), Allaway et al.
patent: 6132987 (2000-10-01), Charo et al.
patent: 6153431 (2000-11-01), Beretta et al.
patent: 6258527 (2001-07-01), Littman et al.
patent: 6265184 (2001-07-01), Gray et al.
patent: 6268477 (2001-07-01), Gray et al.
patent: 6287805 (2001-09-01), Graham et al.
patent: 6344545 (2002-02-01), Allaway et al.
patent: 6448375 (2002-09-01), Samson et al.
patent: 6511826 (2003-01-01), Li et al.
patent: 6528625 (2003-03-01), Wu et al.
patent: 6692938 (2004-02-01), Samson et al.
patent: 6743594 (2004-06-01), Li et al.
patent: 6759519 (2004-07-01), Li et al.
patent: 6797811 (2004-09-01), Gray et al.
patent: 6800447 (2004-10-01), Samson et al.
patent: 6800729 (2004-10-01), Li et al.
patent: 2001/0000241 (2001-04-01), Li et al.
patent: 2002/0048786 (2002-04-01), Rosen et al.
patent: 2002/0061834 (2002-05-01), Rosen et al.
patent: 2002/0076745 (2002-06-01), Li et al.
patent: 2002/0099176 (2002-07-01), Li et al.
patent: 2003/0023044 (2003-01-01), Li et al.
patent: 2003/0100058 (2003-05-01), Roschke et al.
patent: 2003/0166024 (2003-09-01), Rosen et al.
patent: 2004/0151719 (2004-08-01), Li et al.
patent: 2146328 (1994-05-01), None
patent: 2128208 (1994-06-01), None
patent: 2247989 (1997-09-01), None
patent: 0 671 391 (1995-09-01), None
patent: 0 612 723 (1997-08-01), None
patent: 0 834 564 (1998-05-01), None
patent: 0 945 464 (1999-09-01), None
patent: 0 979 655 (2000-02-01), None
patent: 2 771 423 (1999-05-01), None
patent: 10-179180 (1998-07-01), None
patent: 11-243960 (1999-09-01), None
patent: 11-292795 (1999-10-01), None
patent: 2126048 (1999-02-01), None
patent: WO 92/01810 (1992-02-01), None
patent: WO 94/11504 (1994-05-01), None
patent: WO 95/19436 (1995-07-01), None
patent: WO 96/22371 (1996-07-01), None
patent: WO 96/23068 (1996-08-01), None
patent: WO 96/38559 (1996-12-01), None
patent: WO 96/39437 (1996-12-01), None
patent: WO 97/00960 (1997-01-01), None
patent: WO 97/19696 (1997-06-01), None
patent: WO 97/21812 (1997-06-01), None
patent: WO 97/22698 (1997-06-01), None
patent: WO 97/25340 (1997-07-01), None
patent: WO 97/28258 (1997-08-01), None
patent: WO 97/32019 (1997-09-01), None
patent: WO 97/35881 (1997-10-01), None
patent: WO 97/37005 (1997-10-01), None
patent: WO 97/41225 (1997-11-01), None
patent: WO 97/41230 (1997-11-01), None
patent: WO 97/44055 (1997-11-01), None
patent: WO 97/45543 (1997-12-01), None
patent: WO 97/46697 (1997-12-01), None
patent: WO 97/47318 (1997-12-01), None
patent: WO 97/47319 (1997-12-01), None
patent: WO 97/49424 (1997-12-01), None
patent: WO 98/00535 (1998-01-01), None
patent: WO 98/02151 (1998-01-01), None
patent: WO 98/05798 (1998-02-01), None
patent: WO 98/11218 (1998-03-01), None
patent: WO 98/14480 (1998-04-01), None
patent: WO 98/15569 (1998-04-01), None
patent: WO 98/17308 (1998-04-01), None
patent: WO 98/18826 (1998-05-01), None
patent: WO 98/20166 (1998-05-01), None
patent: WO 98/25604 (1998-06-01), None
patent: WO 98/25605 (1998-06-01), None
patent: WO 98/25617 (1998-06-01), None
patent: WO 98/27815 (1998-07-01), None
patent: WO 98/30218 (1998-07-01), None
patent: WO 98/31364 (1998-07-01), None
patent: WO 98/34945 (1998-08-01), None
patent: WO 98/42354 (1998-10-01), None
patent: WO 98/44158 (1998-10-01), None
patent: WO 98/51705 (1998-11-01), None
patent: WO 98/54317 (1998-12-01), None
patent: WO 98/55873 (1998-12-01), None
patent: WO 98/56421 (1998-12-01), None
patent: WO 98/58536 (1998-12-01), None
patent: WO 98/58966 (1998-12-01), None
patent: WO 99/01127 (1999-01-01), None
patent: WO 99/04794 (1999-02-01), None
patent: WO 99/06561 (1999-02-01), None
patent: WO 99/08703 (1999-02-01), None
patent: WO 99/09984 (1999-03-01), None
patent: WO 99/12416 (1999-03-01), None
patent: WO 99/13112 (1999-03-01), None
patent: WO 99/14378 (1999-03-01), None
patent: WO 99/17773 (1999-04-01), None
patent: WO 99/23107 (1999-05-01), None
patent: WO 99/23253 (1999-05-01), None
patent: WO 99/24065 (1999-05-01), None
patent: WO 99/24553 (1999-05-01), None
patent: WO 99/27122 (1999-06-01), None
patent: WO 99/27939 (1999-06-01), None
patent: WO 99/28474 (1999-06-01), None
patent: WO 99/32100 (1999-07-01), None
patent: WO 99/32138 (1999-07-01), None
patent: WO 99/33989 (1999-07-01), None
patent: WO 99/36518 (1999-07-01), None
patent: WO 99/38514 (1999-08-01), None
patent: WO 99/43711 (1999-09-01), None
patent: WO 99/46372 (1999-09-01), None
patent: WO 99/51751 (1999-10-01), None
patent: WO 99/53033 (1999-10-01), None
patent: WO 99/62535 (1999-12-01), None
patent: WO 99/66944 (1999-12-01), None
patent: WO 99/67429 (1999-12-01), None
patent: WO 00/02045 (2000-01-01), None
patent: WO 00/05265 (2000-02-01), None
patent: WO 00/06085 (2000-02-01), None
patent: WO 00/06146 (2000-02-01), None
patent: WO 00/06153 (2000-02-01), None
patent: WO 00/08043 (2000-02-01), None
patent: WO 00/09525 (2000-02-01), None
patent: WO 00/10965 (2000-03-01), None
patent: WO 00/14220 (2000-03-01), None
patent: WO 00/15663 (2000-03-01), None
patent: WO 00/15785 (2000-03-01), None
patent: WO 01/58915 (2001-08-01), None
patent: WO 01/58916 (2001-08-01), None
patent: WO 01/96388 (2001-12-01), None
patent: WO 02/064612 (2002-08-01), None
patent: WO 03/075944 (2003-09-01), None
patent: WO 2004/020468 (2004-03-01), None
Chuntharapai, Generation of Monoclonal Antibodies to Chemokine Receptors, 1997, Methods in Enzymology 288:15-27.
Alkhatib, G. et al., “CC CKR5: A RANTES, MIP-1α, MIP-1β, Receptor as a Fusion Cofactor for Macrophage -Tropic HIV-1,”Science 272:1955-1958, American Association for the Advancement of Science (1996).
Baba, M., et al., “A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV activity,”Proc. Natl. Acad. Sci. U.S.A. 96:5698-5703, National Academy of Sciences (1999).
Balter, M., “Elusive HIV-Suppressor Factors Found,”Science 270:1560-1561, American Association for the Advancement of Science (1995).
Balter, M., “A Second Coreceptor for HIV In Early Stages of Infection,”Science 272:1740, American Association for the Advancement of Science (1996).
Bendig, M.M., “Humanization of Rodent Monoclonal Antibodies by CDR Grafting,”Methods 8:83-93, Academic Press, Inc. (1995).
Björndal, A., et al., “Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype,”J. Virol. 71(10):7478-7487, American Society for Microbiology (1997).
Blanpain, C., et al., “Multiple charged and aromatic residues in
Roschke Viktor
Rosen Craig A.
Ruben Steven M.
Human Genome Sciences Inc.
Sterne Kessler Goldstein & Fox PLLC
Ulm John
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