Human G-protein chemokine receptor (CCR5) HDGNR10

Details Human G-protein chemokine receptor (CCR5) HDGNR10 Human G-protein chemokine receptor (CCR5) HDGNR10

2007-01-09

2007-01-09

Turner, Sharon (Department: 1649)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

C435S325000, C435S326000, C530S387100

Reexamination Certificate

active

10232686

ABSTRACT:
Human G-protein chemokine receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the underexpression and overexpression of the G-protein chemokine receptor polypeptides, respectively. Also disclosed are diagnostic methods for detecting a mutation in the G-protein chemokine receptor nucleic acid sequences and detecting a level of the soluble form of the receptors in a sample derived from a host.

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