Human estrogen receptor-β

Details Human estrogen receptor-β Human estrogen receptor-β

2007-01-02

2007-01-02

Nickol, Gary B. (Department: 1646)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S069100, C435S069700, C435S235100, C435S325000, C435S320100, C435S170000, C435S252300, C435S455000, C530S350000

Reexamination Certificate

active

08906365

ABSTRACT:
The present invention provides isolated nucleic acids encoding full-length human estrogen receptor-β (hERβ), which comprises 530 amino acids. The invention also provides isolated hERβ polypeptides and hERβ-reactive antibodies, including those that specifically recognize amino acids 1–45 of hERβ. The invention also encompasses methods for identifying hERβ-interactive compounds, including agonists, antagonists, and co-activators.

REFERENCES:
patent: 6680368 (2004-01-01), Mosselman et al.
patent: 0 798 378 (1997-10-01), None
patent: WO 99/12961 (1989-03-01), None
patent: WO97/09348 (1997-03-01), None
patent: WO 99/11760 (1999-03-01), None
Kuiper et al.,Proc.Natl.Acad.Sci.USA 93:5925, 1996.
Mosselman et al.,FEBS Letts. 392:49, 1996.
Matteucci et al., 1981,J. Am. Chem. Soc.103:3185.
Yoo et al., 1989,J. Biol. Chem.764:17078.
Merrifield, 1963,J. Am. Chem. Soc.85:2149.
Mayer and Walker, 1987,Immunochemical Methods in Cell and Molecular Biology, (Academic Press, London).
Moore et al., GenBank Accession No. AF051427(Jul. 14, 1999; submitted Feb. 25, 1998)( referencing Biochem. Biophys. Res. Commun. (1998), 274(1): 75-78).
Ogawa, S., “Direct Submission,” GenBank Accession No. AB006590 (Feb. 5, 1999; submitted Aug. 13, 1997)(referencing Biochem. Biophys. Res. Commun. 1998), 243(1): 122-126).
Li, L.C. et al., GenBank Accession No. AF191544 (Jan. 12, 2000; submitted Oct. 1, 1999)(referencing unpublished, submitted to Urology, Oct. 1, 1999).
Moore et al., GenBank Accession No. AF060555(Apr. 29, 1998: submitted Apr. 20, 1998)( referencing unpublished, submitted to Molecular Sciences, Apr. 20, 1998).
Lu et al., GenBank Accession No. AF124790(May 27, 1999; submitted Jan. 29, 1999)(referencing unpublished, submitted to Biochemistry, Jan. 29, 1999).
Moore et al., GenBank Accession No. AF051428 (Mar. 17, 1998; submitted Feb. 25, 1998) (referencing unpublished, submitted to Molecular Sciences, Feb. 25, 1998).
Sieste Mosselman, et al., ERβ Identification and Characterization of a Novel Human Estrogen Receptor, FEBS, vol. 3902/1, 49-53 (1996).

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