Human erythropoietin gene; high level expression in stably trans

Details Human erythropoietin gene; high level expression in stably trans Human erythropoietin gene; high level expression in stably trans

1993-10-06

1997-11-18

Martinell, James

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 694, 43524021, 536 2351, C12N 1527, C12N 1506, C12N 1516

Patent

active

056886799

ABSTRACT:
The Apa I restriction fragment of the human erythropoietin gene, for producing high titers of biologically active hormone from stably transfected cell lines.

REFERENCES:
patent: 4377513 (1983-03-01), Sugimoto et al.
patent: 4703008 (1987-10-01), Lin
patent: 4751084 (1988-06-01), Feder et al.
patent: 4835260 (1989-05-01), Shoemaker
patent: 5441868 (1995-08-01), Lin
New England Biolabs Catalog, 1995, p. 14.
Thompson et al, Proc. Natl. Acad. Sci. USA 56: 296 (1966) reprinted in Readings in Mammalian Cell Culture, 1973, Pollack (ed.), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp. 144-151.
Busby et al, Nature 316: 271 (1985).
Sylvia Lee-Huang et al.; The Human Erythropoietin-Encoding Gene Contains a CAAT Box, TATA Boxes and Other Transcriptional Regulatory Elements In Its 5' Flanking Region. Pp. 227, 228 and 230 (1993) Gene, vol. 128, 227-236.
Maniatis, et al, Molecular Cloning: A Laboratory Manual, 1982.
Berger, Methods In Enzymology, "Guide To Molecular Cloning Techniques", vol. 152, pp. 696-697, 1987.
Jelkman, Rev. Physiol. Biochem. Pharmacol., vol. 104, pp. 140-149, 1986.
Lin et al. 1985. Proc. Natl. Acad. Sci. USA 82: 7580-7584.
Powell et al. 1985. Blood (Suppl. 1) (Nov.): 159a.

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