Human enzymes of the metalloprotease family

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase

Reexamination Certificate

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C435S226000, C435S006120

Reexamination Certificate

active

11433388

ABSTRACT:
This invention relates to newly identified polypeptides which have zinc metalloprotease activities and are referred to as IGS5, and polynucleotides encoding such polypeptides, to their use in therapy and in identifying compounds which may be stimulators and/or inhibitors which are useful in therapy, and to production of such polypeptides and polynucleotides.

REFERENCES:
patent: 1069188 (2001-01-01), None
patent: WO 00/57750 (2000-08-01), None
Bonvouloir N. et al. Molecular Cloning, Tissue Distribution, and Chromosome Localizatin of MMEL2, a Gene Coding for a Novel Human Member of the Neutral Endopeptidase-24. 11 Family, DNA and Cell Biology, 2001, 20, 493-498.

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