Human enzymes of the metalloprotease family

Details Human enzymes of the metalloprotease family Human enzymes of the metalloprotease family

2006-08-01

2006-08-01

Prouty, Rebecca E. (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

C536S023200, C536S023100, C536S023500, C424S094670, C435S320100, C435S069100, C435S325000, C435S348000, C435S410000, C435S254100, C435S252300

Reexamination Certificate

active

07083965

ABSTRACT:
This invention relates to newly identified polypeptides which have zinc metalloprotease activities and are referred to as IGS5, and polynucleotides encoding such polypeptides, to their use in therapy and in identifying compounds which may be stimulators and/or inhibitors which are useful in therapy, and to production of such polypeptides and polynucleotides.

REFERENCES:
patent: WO 00/57750 (2000-08-01), None
patent: EP 1069188 (2001-01-01), None
Bonvouloir N. et al. Molecular Cloning, Tissue Distribution, and Chromosome Localization of MMEL2, a Gene Coding for a Novel Human Member of the Neutral Endopeptidase-24.11 Family, DNA and Cell Biology, 2001, 20, 493-498.

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