Human ena/VASP-like protein splice variant

Details Human ena/VASP-like protein splice variant Human ena/VASP-like protein splice variant

1998-02-20

1999-06-15

Chan, Christina Y.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 691, 435 912, 4353201, 4352523, 436 94, 530350, 536 235, C12N 1512, C12N 1563, C12N 1570, C12P 1934

Patent

active

059121289

ABSTRACT:
The invention provides a human ena/VASP-like protein splice variant (EVL1) and polynucleotides which identify and encode EVL1. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of EVL 1.

REFERENCES:
Adams, M.D., et al., GenBank Accession No. AA312190, cross reference to Nature 377, supp 28:3-17, Apr. 1997.
Naeve, C.W., et al., Accuracy of Automated DNA sequencing: a multi-laboratory comparison of sequencing results. Biotechniques. 19(3):448-453, 1995.
Gertler, F.B. et al, GenBank Accession No. U72519, cross referenced to Cell 87(2):227-239 (1996).
Gertler, F.B. et al., "Mena, a Relative of VASP and Drosophila Enabled, Is Implicated in the Control of Microfilament Dynamics" Cell (1996) 87:227-239.
Ermekova, K.S. et al., "The WW Domain of Neural protein FE65 Interacts with Proline-rich Motifs in Mena, the Mammalian Homolog of Drosophila Enabled" J.Biol.Chem. (1997) 272:32869-32877.
Linial, M., "Proline clustering in protein from synaptic vesicles" Neuroreport (1994) 5:2009-2015.
Ohta, S. et al., "Differential Display Cloning of a Novel Rat cDNA (RNB6) That Shows High Expression in the Neonatal Brain Revealed a Member of Ena/VASP Family" Biochem.Biophys.Res. Commun. (1997) 237:307-312.
Gertler, F.B. et al., (GI 1644452), GenBank Sequence Database (Accession U72519), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894. (1996).
Walter, U., (GI 624963), GenBank Sequence Database (Accession Z46389), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894. (1995).
Haffner, C. et al., "Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP" EMBO J. (1995) 14:19-27.

Affiliated with

Also associated with

Rating

Human ena/VASP-like protein splice variant does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human ena/VASP-like protein splice variant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human ena/VASP-like protein splice variant will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-401852