Human embryo co-culture system and uses thereof

Details Human embryo co-culture system and uses thereof Human embryo co-culture system and uses thereof

1997-05-22

1998-11-17

Lankford, Jr., Leon B.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of co-culturing cells

435366, 435378, 435404, 435406, 600 33, 600 34, C12N 500, A61B 17435, A61D 700

Patent

active

058375430

ABSTRACT:
The present invention provides a human embryo co-culture system comprising a suspension of cultured human tubal epithelial cells. Also provided is a method of method of improving the pregnancy rate of a female undergoing in vitro fertilization, comprising the steps of: contacting an oocyte from said female with a monolayer of cultured human tubal epithelial cells; inseminating the oocyte; and transferring an embryo back to said female.

REFERENCES:
patent: 5213979 (1993-05-01), First et al.
Bongso and Fong. Current Opinion in Obstet. and Gyn. vol. 5, pp. 585-593, 1993.
Bongso et al. Human Reprod. vol. 8 (8), pp. 1155-1162, 1993.
Bongso et al., Human Reprod. vol. 4 (5), pp. 486-494, 1989.
Henriksen et al. Human Reprod. vol. 5 (1), pp. 25-31, 1990.
Irvine Scientific --Manufacturer's Brochure, 1993.
Hycor Scientific --Manufacturer's Brochure, 1994.

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