Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-08-25
1999-07-13
LeGuyader, John L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435219, 4353201, 435325, 435455, 5303871, 53038815, 536 231, 536 232, 536 235, C12N 1500, C12N 1585, C12Q 168, C07K 1600
Patent
active
059225467
ABSTRACT:
Human KUZ polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Human KUZ polypeptides and polynucleotides in the design of protocols for the treatment of inflammation, neural degeneration, allergic disorders, or other disorders involving a dis-regulation of the substrate cytokines or receptors, among others, and diagnostic assays for such conditions.
REFERENCES:
GenBank Accession No. Z48579.
GenBank Accession No. Z21961.
Howard, L. et al. "Molecular cloning of MADM: a catalytically active mammalian disintegrin etalloprotase expressed in various cell types", Biochem, J. 317,45-50, 1996.
Lunn, C.A., et al., "Purification of ADAM 10 from bovine spleen as a TNF.alpha. convertase", FEBS Letters, 400:333-335,1997.
Fambrough et al., The Cell Surface Metalloprotease/Disintegrin Kuzbanian is Required for Axonal Extension in Drosophila, PNAS 91, 13233-38 (Nov. 1996).
R.F. Doolittle, Of URFS and ORFS, A Primer on How to Analyze Derived Amino Acid Sequences, University Science Books (1986), at p. 7.
Robbins and Cotran, Pathological Basis of Disease, W.B. Saunders Co., Phila (1976), pp. 55, 279, 1530.
Glynn et al., PIR, Accession Nos. S66129, S32205, Jul. 19, 1996.
Ellis Catherine Elizabeth
Jackson Jeffrey Richard
Mayer Ruth Judik
Hecht Elizabeth J.
King William T.
LeGuyader John L.
Shibuya Mark G.
SmithKline Beecham Corporation
LandOfFree
Human disintegrin metalloprotease KUZ gene does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Human disintegrin metalloprotease KUZ gene, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human disintegrin metalloprotease KUZ gene will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2274986