Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1995-01-10
1997-04-22
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
4353201, 435325, 435348, 435358, 435365, 536 231, 536 232, C12N 978, C12N 1563, C12N 1509, C07H 2104
Patent
active
056228511
ABSTRACT:
The present invention is directed to a DNA molecule encoding a gene for human deoxycytidylate deaminase. The DNA molecule comprises 26,764 base pairs. A 1317 base pair 5' untranslated region is followed by exon 1 of 108 base pairs, which is followed by intron 1 of 402 base pairs, which is followed by exon 2 of 136 base pairs, which is followed by intron 2 of 20,303 base pairs, which is followed by exon 3 of 117 base pairs, which is followed by intron 3 of 1357 base pairs, which is followed by exon 4 of 97 base pairs, which is followed by intron 4 of 1554 base pairs, which is followed by exon 5 of 76 base pairs, which is followed by a 3' untranslated region of 1297 base pairs. Methods of using the DNA molecule are also provided.
REFERENCES:
Jackson, R.C., J Biol Chem 253: 7440-7446 (1978).
Chiu, C.S. et al. J Biol Chem 252:8603-8608 (1977).
Xu, Y.-Z. and Plunkett, W., Biochem Pharmacol 44: 1819-1827 (1992).
Maley, F. and Maley, G.F., Cancer Res 21: 1421-1426 (1961).
Gelbard, A.S. et al., Biochim Biophys Acta 182: 564-566 (1969).
Weinberg, G. et al., PNAS USA 78: 2447-2451 (1981).
Ellims, P.H. et al., J Biol Chem 256:6335-6340 (1981).
Maley, G.F. and Maley, F., in Advances in Enzyme Regulation, Weber, G., Ed, vol. 8, pp. 55-71, Pergamon Press, London (1970).
Geraci, G. et al., Biochemistry 6: 183-191 (1967).
Maley, G.F. et al., J Biol Chem 247:931-939 (1972).
Maley, G.F. et al., Biochim Biophys Acta 1162: 161-170 (1993).
Maley, G.F. et al., J Biol Chem 265:47-51 (1990).
Maley, G.F. et al., J Biol Chem 258: 8290-8297 (1983).
McIntosh, E.M. and Haynes, R.H., Mol Cell Biol 6: 1711-1721 (1986).
Maley, Methods Enzymol 12A: 170-182 (1967).
Melton, D.W., Bio Essays 16(9):633-638 (1994).
Hasty, P. et al., Nature 364: 501-506 (1993).
Snouwaert, J.N. et al., Science 257: 1083-1088 (1992).
McMahon, A.P. and Bradley, A., Cell 62:1073-1085 (1990).
Maley, F. and Maley, G.F., Curr Topics Cell Regul 5: 177-228 (1972).
Maley, F. and Maley, G.F., J Biol Chem 235:2968-2970 (1960).
Maley, G.F. and Maley,F., J Biol Chem 234:2975-2980 (1959).
Bianchi, V. et al., Mol Cell Biol 7: 4218-4224 (1987).
de Saint Vincent, B.R. et al., J Biol Chem 255;162-167 (1980).
Sargent, R.G. and Mathews, G.K., J Biol Chem 262: 5546-5553 (1987).
Meuth, M., Exp Cell Res 181: 305-316 (1989).
Weiner, K.X.B. et al., J Biol Chem 268: 12983-12989 (1993).
Weiner, K.X.B. et al, Mol Endocrinol 4: 1249-1256 (1990).
Maley Frank
Maley Gladys R.
Weiner Karen X. B.
Health Research Incorporated
Lau Kawai
Wax Robert A.
LandOfFree
Human deoxycytidylate deaminase gene does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Human deoxycytidylate deaminase gene, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human deoxycytidylate deaminase gene will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-340966