Human deoxycytidine kinase 2

Details Human deoxycytidine kinase 2 Human deoxycytidine kinase 2

1995-06-02

1999-06-22

Carlson, Karen Cochrane

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

43525233, 435325, 4353201, 536 231, 536 232, 536 234, 536 235, C12N 912, C12N 120, C07H 2104

Patent

active

059142588

ABSTRACT:
A human deoxycytidine kinase 2 polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of malignancies and viral infections. Antagonist against such polypeptides and their use as a therapeutic to treat immunodeficiency disorders are also disclosed. Diagnostic assays for detecting diseases related to mutations in the hdCK2 nucleic acid sequence and the concentration of the polypeptide encoded by such nucleic acid sequence is also disclosed.

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