Human D5 dopamine receptor protein

Details Human D5 dopamine receptor protein Human D5 dopamine receptor protein

1995-02-06

1997-11-11

Ulm, John

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

435 691, 530395, 536 235, C07K 14705

Patent

active

056865732

ABSTRACT:
The present invention relates to the isolation, characterization and pharmacological uses for the human D5 dopamine receptor, the gene corresponding to this receptor, pseudogenes of this receptor gene, a recombinant eukaryotic expression vector capable of expressing the human D5 dopamine receptor in cultures of transformed eukaryotic cells and such cultures of transformed eukaryotic cells that synthesize the human D5 dopamine receptor. The invention relates to the biochemical and physiological characterization of the human D5 dopamine receptor and the development and testing of drugs useful for treating or preventing human disease.

REFERENCES:
Grandy et al., P.N.A.S. 88:9175-9179, Oct. 1991.
Sunahara et al., Nature 350:614-619, 18 Apr. 1991.

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