Human cytotoxic T-lymphoctye epitope and its agonist eptiope...

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 8 to 10 amino acid residues in defined sequence

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S300000, C514S019200, C514S019300, C514S021600

Reexamination Certificate

active

07999071

ABSTRACT:
Novel MUC-1 epitopes outside the VNTR region are identified. In addition, the first agonist epitope of MUC-1 is described. The employment of agonist epitopes in peptide, protein and vector-based vaccine may well aid in the development of effective vaccines for a range of human cancers.

REFERENCES:
patent: 5759808 (1998-06-01), Casterman et al.
patent: 5827666 (1998-10-01), Finn et al.
patent: 5861381 (1999-01-01), Chambon et al.
patent: 6001349 (1999-12-01), Panicali et al.
patent: 6123923 (2000-09-01), Unger et al.
patent: 6319496 (2001-11-01), Panicali et al.
patent: 6328969 (2001-12-01), Houghton et al.
patent: 6407063 (2002-06-01), Luiten et al.
patent: 6514942 (2003-02-01), Ionnides et al.
patent: 6531451 (2003-03-01), Chaux et al.
patent: 6534062 (2003-03-01), Raz et al.
patent: 6548068 (2003-04-01), Schlom et al.
patent: 6576896 (2003-06-01), Figeys et al.
patent: 6600012 (2003-07-01), Agrawal et al.
patent: 6602660 (2003-08-01), Agrawal et al.
patent: 7129053 (2006-10-01), Reiter et al.
patent: 2003/0021770 (2003-01-01), Schlom et al.
patent: 2003/0180314 (2003-09-01), DeGroot
patent: 2003/0235868 (2003-12-01), Hoogenboom et al.
patent: 2004/0054137 (2004-03-01), Thomson et al.
patent: 2005/0042209 (2005-02-01), Kufe et al.
patent: 1336850 (2003-08-01), None
patent: WO 00/06723 (2000-02-01), None
patent: WO 01/18035 (2001-03-01), None
patent: WO 01/24810 (2001-04-01), None
patent: WO 01/27612 (2001-04-01), None
patent: WO 0190197 (2001-11-01), None
patent: WO 02/060953 (2002-08-01), None
patent: WO 02/083903 (2002-10-01), None
patent: WO 03/099193 (2003-04-01), None
patent: WO-2005/046614 (2005-05-01), None
patent: WO-2005/046622 (2005-05-01), None
Skolnick and Fetrow. From genes to protein structure and function: novel applications of computational approaches in the genomic era. Trends in Biotechnology, 2000. vol. 18, pp. 34-39.
Burgess, Shaheen, Ravera, Jaye, Donohue, and Winkles. Possible dissociation of the heparin-binding and mitogenic activities of heparin-binding (acidic fibroblast) growth factor-1 from its receptor-binding activities by site directed mutagenesis of a single lysine residue. Journal of Cell Biology, 1990. vol. 111, pp. 2129-2138.
Lazar, Watanabe, Dalton, and Sporn. Transforming growth factor a: mutation of aspartic acid 47 and leucine 48 results in different biological activities. Molecular and Cellular Biology, 1988. vol. 8, pp. 1247-1252.
S. Gendler et al., J. Biol. Chem., 265(25):15286-15293 (1990).
Hareuveni et al., Eur. J. Biochem., 189(3):475-486 (1990).
Lan et al., J. Biol. Chem., 265(25):15294-15299 (1990).
Brossart et al., Blood, 93(12):4309-4317 (1999).
Pietersz et al., Vaccine, 18(19):2059-2071 (2000).
Carmon et al., Int. J. Cancer, 84(3):391-397 (2000).
Heukamp et al., Int. J. Cancer (1(3):385-392 (2001).
BLAST search (SwissProt Analysis): RID: 1063146772-12815-1701048.BLASTQ3, <http://www.ncbi.nlm.nih.gov/blast/Glast.cgi> (2003).
Tsang et al., “A Human Cytotoxic T-Lymphocyte Epitope and Its Agonist Epitope from the Nonvariable Number of Tandem Repeat Sequence of MUC-1,”Clinical Cancer Research, 10: 2139-2149 (2004).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Human cytotoxic T-lymphoctye epitope and its agonist eptiope... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human cytotoxic T-lymphoctye epitope and its agonist eptiope..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human cytotoxic T-lymphoctye epitope and its agonist eptiope... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2698038

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.