Human CR3.alpha./.beta. heterodimers

Details Human CR3.alpha./.beta. heterodimers Human CR3.alpha./.beta. heterodimers

1993-06-16

1995-06-13

Draper, Garnette D.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

435 691, 536 235, C07K 14705

Patent

active

054243998

ABSTRACT:
The invention features human CR3.alpha. recombinant or synthetic peptide capable of inhibiting a CR3-mediated immune response, a purified DNA encoding a human CR3.alpha. peptide, and a method of controlling any phagocyte-mediated tissue damage such as that associated with reduced perfusion of heart tissue during acute cardiac insufficiency. As used herein, a human CR3.alpha. recombinant peptide is a chain of amino acids derived from recombinant CR3.alpha.-encoding cDNA, or the corresponding synthetic DNA.

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