Human cornichon molecule

Details Human cornichon molecule Human cornichon molecule

1997-10-14

1999-10-19

Horlick, Kenneth R.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 691, 435 701, 435 711, 435 912, 4352523, 4353201, 435325, 536 235, 536 2431, C12Q 168, C12P 1934, C07H 2104

Patent

active

059687444

ABSTRACT:
The invention provides a human cornichon protein (CORN) and polynucleotides which identify and encode CORN. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating and preventing disorders associated with expression of CORN.

REFERENCES:
Matoba et al., Gene 146, 199-207 (1994).
Morisato, D. et al., "Signaling Pathways That Establish The Dorsal-Ventral Pattern Of The Drosophila Embryo", Annu. Rev. Genet., 29: 371-399 (1995).
Roth, S. et al., "cornichon and the EGF Receptor Signaling Process Are Necessary for Both Anterior-Posterior and Dorsal-Ventral Pattern Formation in Drosophila", Cell, 81: 967-978 (1995) (GI 886769).
Panayotou, G.N. et al., "Purification of the epidermal growth factor receptor from A431 cells", Receptor Biochemistry, (E.C. Hulme, ed.) IRL Press, Oxford, U.K., pp. 203-211 (1990).

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