Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Glycoprotein – e.g. – mucins – proteoglycans – etc.
Patent
1986-12-08
1990-03-06
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Glycoprotein, e.g., mucins, proteoglycans, etc.
530350, 530351, 530380, 530387, 530806, 530831, C07K 1514, C07K 1516
Patent
active
049067346
ABSTRACT:
Human conglutinin, polyclonal, and monoclonal antibodies raised against human conglutinin, and their uses in therapy and diagnosis are described.
Human conglutinin was obtained from human plasma by affinity chromatography with anti-bovine conglutinin antibody, has a relative molecular weight of 330 and 40 K unreduced and 66 K reduced as measured by SDS-PAGE, shows calcium-dependent and sugar inhibitable binding to complement-reacted immune complexes and zymosan, and immunological cross-reaction with anti-bovine conglutinin antibody.
REFERENCES:
patent: 4239746 (1980-12-01), Bartos et al.
patent: 4342566 (1982-08-01), Theofilopoulos et al.
patent: 4427779 (1984-01-01), Reckel et al.
patent: 4503035 (1985-03-01), Pestka et al.
patent: 4548909 (1985-10-01), Parratt
Ross et al., J. Immunol., 134(5), 3307-15, 1985, (May).
Eggert et al., Chem. Abs., 91:105628t, 1979.
Tamura et al., Biological Abs., 71, 59809, 1980.
Hautanen et al., Chem. Abs., 92, 56616x, 1980.
Jensenius et al., Chem. Abs., 104:128021r, 1985, (pub. date of original reference).
Samual et al., Biol. Abs., 82, 111882, 1986.
Gupta et al., Biol. Abs., 73(5), 32120, 1981.
P. J. Lachmann et al., Chemical Abstract No. 88337k, 72(17):199, (Apr. 1970).
C. G. Durand et al., Chemical Abstract No. 228186e, 101(25):578, (Dec. 1984).
K. R. Mittal et al., Chemical Abstract No. 113437x, 79(19):184, (Nov. 1973).
R. A. Eisenberg et al., Jour. Immunol., 118(4):1428-1434, (Apr. 1977).
Jensenius et al., Biosci. Rep., 5(10-11): 901-5, (1985).
Eggert, Biochem. Soc. Trans., 7: 193-194, (1979).
Thiel et al., Scand. J. Immunol., 26: 461-468, (1987).
Sage et al., J. Immunol., 90: 347-357, (1963).
Lachmann et al., Immunochemistry, 1: 37-41, (1964).
Eggert, Int. Arch. Allergy Appl. Immun., 61: 192-202, (1980).
Eggert, Int. Arch. Allergy Appl. Immun., 61: 203-212, (1980).
Eggert, Int. Arch. Allergy Appl. Immun., 62: 34-45, (1980).
Lachmann, Adv. Immunol., 6: 479-527, (1967).
Baatrup et al., Scand. J. Immunol., 26: 355-361, (1987).
Lachmann, Immunology, 5: 687-705, (1962).
Davis et al., Biochemistry, 23: 2139-2144, (1984).
Dunker et al., J. Biol. Chem., 244: 5047, (1969).
Allison et al., PNAS U.S.A., 75: 3953, (1978).
Coombs, et al., "The Serology of Conglutinin and Its Relation to Disease," Blackwell Sci. Pub., Oxford, Adler & Sons Ltd., Bartholomew Press, Dorking, (1961), pp. 46-50, 128-137 and 184-194.
Lachmann et al., J. Immunol., 100: 691-698, (1968).
Hirani et al., J. Immunol., 134(2): 1105-1109.
Ingram, D. G., (1972), "Biological Aspects of Conglutinin and Immunoconglutinins," Biological Activities of Complement, Kager, Basel, pp. 215-228.
Ingram, D. G., Immunol., 2: 322-333, (1959a).
Ingram, D. G., Immunol., 2: 334-335, (1959b).
Casali et al., Clin. Exp. Immunol., 37: 295-309, (1979).
Barta et al., J. Immunol., 105: 350, (1970).
Jonas, et al., Vet. Immunol. Immunopathol., 5: 289, (1983/84).
Kawasaki et al., J. Biochem., 98: 1309-1320, (1985).
Leon et al., Science, 143: 1327-1328, (1964).
Linscott et al., J. Immunol., 121(2): 658-664, (1978).
Stankiewicz et al., Archivum Immunologiae Therapiae Experimentalis, 33: 423-428, (1985).
Strang et al., Biochem. J., 234: 381-389, (1986).
Tlaskalova et al., Folia Microbiol., (Prague), 13: 450-458, (1968).
Brown et al., J. Immunol., 128(2): 860-865, (1982).
Lachmann et al., "Conglutinin and Immunoconglutinins," pp. 204-214 in Biological Activities of Complement, ed., D. G. Ingram, (Karger, Basel, 1972).
Coombs et al., J. Hyg. Camb., 48: 484-499, (1950).
Kushan Jeff
Moskowitz Margaret
Novo Industri A/S
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