Human chorionic gonadotropin releasing factor

Details Human chorionic gonadotropin releasing factor Human chorionic gonadotropin releasing factor

1986-05-15

1990-07-31

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435219, 435267, 435268, 435269, 435272, C12N 964

Patent

active

049450557

ABSTRACT:
A substantially purified human chorionic gonadotropin releasing factor (hCG-RF) which is a glycoprotein with a molecular weight between about 50,000 and about 70,000. This hCG-RF is capable of stimulating release of human chorionic gonadotropin as well as prostaglandins, particularly from human term placental cultures. This hCG-RF is capable of degrading GnRH and is isolatable from human placenta, preferably term placenta. Such hCG-RF may be used to affect a state of pregnancy, particularly mammalian pregnancy. This effect upon pregnancy may comprise the induction of a normal labor.

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