Human chitinase, its recombinant production, its use for...

Details Human chitinase, its recombinant production, its use for... Human chitinase, its recombinant production, its use for...

2005-05-24

2005-05-24

Prouty, Rebecca (Department: 1652)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

C435S209000, C435S404000, C435S182000, C435S007400, C435S018000, C424S401000, C424S422000, C424S418000, C426S580000, C426S582000, C426S656000, C426S657000

Reexamination Certificate

active

06896884

ABSTRACT:
A new human chitinase having an amino acid sequence as shown in FIG.1or FIG.2. Modified forms of it having a similar chitin-hydrolyzing activity, and antigenic peptides representing one of its epitopes. Recombinant production of the human chitinase by genetically engineered hosts or host cells. Recombinant nucleic acid encoding it, and human chitinase-specific oligonucleotides. Use for therapeutic or prophylactic treatment of humans against infection by chitin-containing pathogens, or for decomposing chitin, e.g. from chitin-based articles. Antibodies binding to the human chitinase. Diagnostic test kits comprising the human chitinase, its antigenic peptides, human chitinase antibodies, recombinant nucleic acid or oligonucleotides.

REFERENCES:
Overdijk et al. “Human Serum Contains a Chitinase: Identification of an Enzyme, Formerly Described as 4-Methylumbelliferyl-tetra-N-Acetylchilotetraoside Hydrolase (MU-TACT Hydrolase)” Glycobiology 4(6): 797-803. (1994).*
D.A.L. Davies et al. “Mycolase, A New Kind of Systemic Antimycotic”, Nature 273: 235-236. (May 1978).*
A.M.S. Pope et al. “The Influence of Carbonhydrases on the Growth of Fungal Pathogens in vitro and in vivo”, Postgraduate Med. J. 55: 674-676 (Sep. 1979).*
Boot et al., The Journal of Biological Chemistry 270 (44) : 26252-26256 (Nov. 1995).
Renkema et al., The Journal of Biological Chemistry 270 (5) : 2198-2202 (Feb. 1995).
Hakala et al., The Journal of Biological Chemistry 268 (34) : 25803-25810 (Dec. 1993).
Kramer et al.,Insect Biochemistry and Molecular Biology23(6) : 691-701 (1993). Abstract only.
1988 Stratagene Catalog, p. 39 (1988).

Affiliated with

Also associated with

Rating

Human chitinase, its recombinant production, its use for... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human chitinase, its recombinant production, its use for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human chitinase, its recombinant production, its use for... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3400758