Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Reexamination Certificate
2005-08-30
2005-08-30
Mertz, Prema (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
C424S085100, C536S023500, C435S069500, C530S402000
Reexamination Certificate
active
06936688
ABSTRACT:
Human chemokine Beta-10 polypeptides and DNA (RNA) encoding such chemokine polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such chemokine polypeptides for the treatment of leukemia, tumors, chronic infections, autoimmune disease, fibrotic disorders, wound healing and psoriasis. Antagonists against such chemokine polypeptides and their use as a therapeutic to treat rheumatoid arthritis, autoimmune and chronic inflammatory and infective diseases, allergic reactions, prostaglandin-independent fever and bone marrow failure are also disclosed.
REFERENCES:
patent: 5278287 (1994-01-01), Rollins et al.
Adams Mark D.
Alderson Ralph
Appelbaum Edward R.
Gentz Solange H. L.
Li Haodong
Human Genome Sciences Inc.
Human Genome Sciences Inc.
Mertz Prema
SmithKline Beecham Corp.
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