Human cDNAs and proteins and uses thereof

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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C514S012200, C435S007100

Reexamination Certificate

active

07122629

ABSTRACT:
The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be used in screening and diagnosis assays for abnormal GENSET expression and/or biological activity and for screening compounds that may be used in the treatment of GENSET-related disorders.

REFERENCES:
patent: WO 99/45031 (1999-09-01), None
patent: WO 00/55174 (2000-09-01), None
Kasinrerk, W., et al., NCBI Submission Accession No. P35613.
Yoshida et al., Homo-oligomer formation by basigin, an immunoglobulin superfamily member, via its N-terminal immunoglobulin domain, Eur J Biochem. Jul. 2000;267(14):4372-80.□□.
Yurchencko et al., Active site residues of cyclophilin A are crucial for its signaling activity via CD147, □□J Biol Chem. Jun. 21, 2002;277(25):22959-65. Epub Apr. 9, 2002.
Sun et al., Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions, Cancer Res. Mar. 1, 2001;61(5):2276-81□□.
Guo, H., et al.; “Stimulation of Matrix Metalloproteinase Production by Recombinant Extracellular Matrix Metalloproteinase Inducer from Transfected Chinese Hamster Ovary Cells”; The Journal of Biological Chemistry; vol. 272, No. 1, Jan. 3, 1997; pp. 24-27; The American Society for Biochemistry and Molecular Biology, Inc.
Pushkarsky, T., et al.; “CD147 facilitates HIV-1 Infection by interacting with virus-associated cyclophillin A”; PNAS,May 22, 2001; vol. 98, No. 11; pp. 6360-6365.
Accession No. X64364 S40605; Stockinger, H.; Submitted (Feb. 5, 1992), Inst of Immunology-Virce.
Accession No. AC005559 AC005577; Lamerdin, J.E., et al.; “Sequence analysis of a 3.5 Mb contig inhuman 19p13.3 containing a serine protease gene cluster”; Submitted (Aug. 29, 1998) Joint Genome Institute, Lawrence Livermore National Laboratory.

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